Carbimazole
Last updated: 08/04/2021
(Also known as: athyromazole; carbethoxymethimazole; carbinazole )
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
A prodrug of methimazole used to treat hyperthyroidism
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Cats, Dogs
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C₇H₁₀N₂O₂S
CCOC(=O)N1C=CN(C1=S)C
No data
CFOYWRHIYXMDOT-UHFFFAOYSA-N
InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
carbimazole
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Anti-thyroid drug, Prodrug, Thionamide
Thioamide
97%
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Synthetic
Thyroid peroxidase inhibitor
[Thyroid peroxidase, antagonist]
22232-54-8
244-854-4
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QH03BB01
Systemic hormone preparations excluding sex hormones & insulins: Thyroid therapy
No
No data
186.23
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ethyl 3-methyl-2-sulfanylidene-imidazole-1-carboxylate
3-methyl-2-thioxo-4-imidazoline-1-carboxylic acid ethyl ester
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White to yellowish-white crystalline powder
Vidalta 10mg tablets for cats
Intervet UK Ltd
UK National authorisation
Prescription only medicine to be authorised by a veterinarian (POM-V)
Vidalta 15mg tablets for cats
Intervet UK Ltd
UK National authorisation
Prescription only medicine to be authorised by a veterinarian (POM-V)
Usually supplied in tablet form for oral administration
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123
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130
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3.39 X 1000
Calculated
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0.53
Low
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1.04
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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In water: 291nm In acid: 227nm & 291nm
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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Soil adsorption and mobility
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Known soil and groundwater metabolites
None
thiamazole Note: Pharmacologically active
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Human; Animal
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Terrestrial ecotoxicology
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HUMAN HEALTH AND PROTECTION
High (class III)
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May be absorbed through the skin
Excreted in the urine as thiamazole or its metabolites
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May cause skin rashes May cause bone marrow suppression May cause hair loss
Emits toxic fumes under fire conditions
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Not listed (Not listed)
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carbimazole
carbimazol
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carbimazol
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Record last updated:
08/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242