Pipemidic acid
Last updated: 17/08/2023
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
An antibacterial drug effective against Gram-negative and certain Gram-positive bacteria
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C₁₄H₁₇N₅O₃
CCN1C=C(C(=O)C2=CN=C(N=C21)N3CCNCC3)C(=O)O
No data
JOHZPMXAZQZXHR-UHFFFAOYSA-N
InChI=1S/C14H17N5O3/c1-2-18-8-10(13(21)22)11(20)9-7-16-14(17-12(9)18)19-5-3-15-4-6-19/h7-8,15H,2-6H2,1H3,(H,21,22)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
pipemidic acid
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Antibacterial, Antibiotic, Medicinal drug
Quinolone
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Synthetic
Acts by inhibiting bacterial DNA gyrase-dependent processes
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51940-44-4
257-530-2
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QJ01MB04
Antiinfectants for systemic use: Antibacterials for system use
No
No data
303.32
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8-ethyl-5-oxo-2-piperazin-1-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
5,8-dihydro-8-ethyl-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid
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Off-white coloured powder
None identifid
None identified
No UK authorisation for use with animals
Not applicable
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322
Moderate
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253
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535
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277
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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7.94 X 10-03
Calculated
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-2.1
Low
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0.95
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3.80 X 10-08
Low volatility
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Soil adsorption and mobility
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Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
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None
Terrestrial ecotoxicology
16000
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Rat
Low
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> 151
R4 R = Peer reviewed scientific publications 4 = Verified data
Scenedesmus vacuolatus
Low
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HUMAN HEALTH AND PROTECTION
High (class III)
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16000
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Rat
Low
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Subcutaneous LD₅₀ = 1438 mg kg⁻¹
Rat
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Intravenous LD₅₀ = 529 mg kg⁻¹
Rat
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Between 25 and 88% of orally administered dose is excreted into urine as a bacteriologically act metabolite, other loses occurs via faeces and bile
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E1 E = Unspecified genotoxicity type (miscellaneous data source) 1 = Positive
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
✓Yes, known to cause a problem
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May be harmful is swallowed or inhaled Possible kidney and liver toxicant May cause gastrointestinal problems
No information available
Health: H317, H334
Not listed (Not listed)
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pipemidic acid
acide pipemidique
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acido pipemidico
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Record last updated:
17/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242