Aminitrozole (Ref: CL 5279)
Last updated: 30/08/2023
(Also known as: Nithiamide; 2-acetamido-5-nitrothiazole; nitazole)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A drug shown to be active in vitro against bacteroides, peptococci, peptostreptococci, clostridia, staphylococci, colibacilli and streptococci
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Turkeys
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C₅H₅N₃O₃S
CC(=O)NC1=NC=C(S1)[N+](=O)[O-]
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UJRRDDHEMZLWFI-UHFFFAOYSA-N
InChI=1S/C5H5N3O3S/c1-3(9)7-5-6-2-4(12-5)8(10)11/h2H,1H3,(H,6,7,9)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
aminitrozole
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Antiprotozoal, Antibacterial, Antimicrobial, Medicinal drug
Imidazole
>98%
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Synthetic
Inhibts microorganism growth
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140-40-9
205-414-7
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8798
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No
No data
187.18
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N-(5-nitro-1,3-thiazol-2-yl)acetamide
2-acetylamino-5-nitrothiazole
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Yellowish coloured crystalline solid
None identified
None identified
No UK authorisation for use with animals
Not applicable
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1610
High
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263
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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304
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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137.5
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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2.00 X 1001
Calculated
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1.3
Low
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1.598
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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0.247
Low volatility
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Soil adsorption and mobility
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Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
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None
Terrestrial ecotoxicology
> 400
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Rat
Moderate
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> 600
Meleagris gallopavo
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 400
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Rat
Moderate
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Intraperitoneal LD₅₀ > 200 mg kg⁻¹
Rat
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Subcutaneous LD₅₀ > 3200 mg kg⁻¹
Mouse
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
May cause headache, nausea, general malaise & dizuria
May explosively decompose on heating, shock, friction, etc. Light sensitive Do not mix with oxidising compounds
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Not listed (Not listed)
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aminitrozole
amminitrozol
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amminitrozol
amminitrozol
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Record last updated:
30/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242