Ipronidazole
Last updated: 17/08/2023
(Also known as: Ro-7-1554; IPZ)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An antiprotozoal veterinary drug used, for example, for the treatment of histomoniasis in turkeys and for swine dysentery
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Turkeys, Pigs
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C₇H₁₁N₃O₂
CC(C)C1=NC=C(N1C)[N+](=O)[O-]
No data
NTAFJUSDNOSFFY-UHFFFAOYSA-N
InChI=1S/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
ipronidazole
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Antiprotozoal; Medicinal drug; Feed additive; Anthelmintic; Coccidiostat
Nitroimidazole
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Synthetic
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14885-29-1
238-957-3
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QP51AA10
Antiparasitic products, insecticides & repellents: Antiprotozoals
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Not listed
169.18
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2-isopropyl-1-methyl-5-nitro-1H-imidazole
1-methyl-5-(1-methylethyl)-2-nitro-1H-imidazole
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White crystalline plates
1740
High
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60
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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2.29 X 1001
Calculated
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1.36
Low
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Soil adsorption and mobility
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Low risk
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Based on LogP < 3
Low risk
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Known soil and groundwater metabolites
None
1-methyl-2-(2-hydroxyisopropyl)-5-nitroimadazole (Ref: -)
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Rats (Faeces)
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2,3-dihydro-2-(2-hydroxypropyl)-3-methyl-4-nitro-1H-imidazol-5-ol (Ref: -)
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Rats (Faeces)
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5-isopropyl-1-methyl-2-nitro-1H-imidazole (Ref: -)
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Dogs (Urine)
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2-isopropyl-1-methyl-5-nitro-1H-imidazole (Ref: -)
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Dogs (Urine)
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Terrestrial ecotoxicology
920
Rat
Moderate
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640
Meleagris gallopavo
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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920
Rat
Moderate
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Excreted in the urine (~27%), bile (34%) and faeces (31%)
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E2 E = Unspecified genotoxicity type (miscellaneous data source) 2 = Mixed/ambiguous results
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
No further information available
No information available
Health: H302
Not listed (Not listed)
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ipronidazole
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ipronidazol
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Record last updated:
17/08/2023
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242