Albaconazole (Ref: UR-9825)
Last updated: 21/07/2022
(Not known by any other names)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
 
 
An antifungal agent that has also shown very potent activity against species of Candida, Cryptococcus and Aspergillus. It also demonstrates anti-parasitic activity and is effective against Chagas disease.
Novel
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Dogs; Monkeys
Isomeric
C₂₀H₁₆ClF₂N₅O₂
CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
UHIXWHUVLCAJQL-MPBGBICISA-N
InChI=1S/C20H16ClF2N5O2/c1-12(28-11-25-18-6-13(21)2-4-15(18)19(28)29)20(30,8-27-10-24-9-26-27)16-5-3-14(22)7-17(16)23/h2-7,9-12,30H,8H2,1H3/t12-,20-/m1/s1
Yes
Antifungal agent; Antiparasitic
Triazole fungicide; Conazole fungicide
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Synthetic
The drug blocks a number of CYP450 liver enzymes.
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187949-02-6
642-950-4
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208952
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431.83
(1R,2R)-7-Chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one
(1R,2R)-7-Chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one
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White to pale yellow solid
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125
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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659
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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352
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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1.00 X 1003
Calculated
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3.0
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
Moderate
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1.5
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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1.667
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Soil adsorption and mobility
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None
Terrestrial ecotoxicology
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HUMAN HEALTH AND PROTECTION
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Carcinogen
Endocrine disruptor
No data found
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
No data found
No data found
Eye irritant
Phototoxicant
 
No data found
No data found
 
No information available
No information available
Health: H302
Not listed (Not listed)
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albaconazole
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Record last updated:
21/07/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242