Acynonapyr (Ref: NA-89)
Last updated: 14/03/2024
(Not known by any other names)
Acynonapyr is an insecticide used to selectively control spider mite. Little has currently been published regarding its environmental fate and behaviour. Acynonapyr is toxic to fish. It is not highly toxic to mammals either via ingestion or in contact with the skin. It is reported to have developmental effects and may be a liver and kidney toxicant.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
An insecticide and acaricide that is currently registered in Japan
Spider mites
Vegetables; Tea; Citrus; Cut flowers; Almond; Pome fruit; Hops; Turf
-
Novel; Current
2019, registered Japan
Not approved
Not applicable
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Not applicable
Not applicable
Not applicable
No
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
ISIceland
NONorway
 
 
 
 
 
 
 
 
 
Racemic. The (S)-enantiomer is the most active.
C₂₄H₂₆F₆N₂O₃
CCCOC1=C(C=CC(=C1)C(F)(F)F)OC2CC3CCCC(C2)N3OC4=NC=C(C=C4)C(F)(F)F
CCCOC1=C(C=CC(=C1)C(F)(F)F)OC2C[C@H]3CCC[C@@H](C2)N3OC4=NC=C(C=C4)C(F)(F)F
GIDAJLLAARKRMS-BWTSREIZSA-N
InChI=1S/C24H26F6N2O3/c1-2-10-33-21-11-15(23(25,26)27)6-8-20(21)34-19-12-17-4-3-5-18(13-19)32(17)35-22-9-7-16(14-31-22)24(28,29)30/h6-9,11,14,17-19H,2-5,10,12-13H2,1H3/t17-,18+,19+
Yes
Insecticide, Acaricide
Unclassified pesticide
-
-
Synthetic
Acts on inhibitory glutamate receptors and disrupts neurotransmission. Calcium-activated potassium channel (KCa2) modulator.
1332838-17-1
696-576-1
None allocated
-
132115472
No data found
504.47
(1R,3r,5S)-3-(2-propoxy-4-(trifluoromethyl)phenoxy)-9-((5-(trifluoromethyl)pyridin-2-yl)oxy)-9-azabicyclo(.3.1)nonane
3-endo-(2-propoxy-4-(trifluoromethyl)phenoxy)-9-((5-(trifluoromethyl)-2-pyridyl)oxy)-9-azabicyclo(3.3.1)nonane
(3-endo)-3-(2-propoxy-4-(trifluoromethyl)phenoxy)-9-((5-(trifluoromethyl)-2-pyridinyl)oxy)-9-azabicyclo(3.3.1)nonane
-
-
Not applicable
Not applicable
33
Not applicable
-
Pale yellow solid with slight aromatic odour
Usually formulated as an emulsifiable concentrate
0.004
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
at 30 °C
Low
-
-
-
77.2
E4 E = Manufacturers safety data sheets 4 = Verified data
-
Degrades before boiling
E4 E = Manufacturers safety data sheets 4 = Verified data
-
165
E4 E = Manufacturers safety data sheets 4 = Verified data
-
-
-
-
4.47 X 1006
Calculated
-
6.65
E4 E = Manufacturers safety data sheets 4 = Verified data
at 25 °C
High
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-
-
-
-
-
1.5
E4 E = Manufacturers safety data sheets 4 = Verified data
-
-
-
-
-
8.3 X 10-08
E4 E = Manufacturers safety data sheets 4 = Verified data
Low volatility
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Soil adsorption and mobility
-
-
-
Cannot be calculated
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-
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None
Terrestrial ecotoxicology
> 2000
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
Low
-
-
-
-
-
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-
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0.021
E4 E = Manufacturers safety data sheets 4 = Verified data
Oncorhynchus mykiss
High
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HUMAN HEALTH AND PROTECTION
High (class III)
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> 2000
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
Low
2000
E4 E = Manufacturers safety data sheets 4 = Verified data
Rat
-
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EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
✓Yes, known to cause a problem
No data found
XNo, known not to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
XNo, known not to cause a problem
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Possible liver, lung and lymph node toxicant Body weight suppressant
No information available
Environment: H400
Not listed (Not listed)
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acynonapyr
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Record last updated:
14/03/2024
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242