Chlorpyrifos-methyl (Ref: OMS 1155) |
Last updated: 23/08/2024 |
(Also known as: ENT 27520; Dowco 214; chlorpyriphos-methyl; chlorpyrifos-me) |
SUMMARY |
An organophosphate broad-spectrum insecticide. It has a low aqueous solubility, is quite volatile and is non-mobile. There is a low risk of leaching to groundwater based on its chemical properties. It tends not to be persistent in soil or water systems. It is not highly toxic to mammals but is classified as an acetyl cholinesterase inhibitor and a neurotoxicant. It is also a skin irritant and sensitiser. It is highly toxic to fish, aquatic invertebrates and honeybees and moderately toxic to birds, aquatic plants, algae and earthworms. |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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An insecticide and acaricide used to control soil and foliage pests | |
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Scale; Wooly aphid; Leaf roller; Caterpillars; Cutworms; Rootworms; Cockroaches; Flea beetles; Flies; Termites; Fire ants | |
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Grains; Cotton; Fruit including apples, pears, grapes, pineapples, bananas, strawberries, mango; Tomatoes; Nuts; Vegetables including carrots, cabbages, cauliflower | |
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Chlorpyrifos has been used very successfully over a long period of time to control a wide range of foliar pests on agricultural crops. | |
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Current | |
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1966, first reported; 1985, first marketed USA |
GB regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use as a pesticide |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Spain/Poland | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Chemical structure |
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None | |
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C₇H₇Cl₃NO₃PS | |
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COP(=S)(OC)OC1=NC(=C(C=C1Cl)Cl)Cl | |
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No data | |
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HRBKVYFZANMGRE-UHFFFAOYSA-N | |
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InChI=1S/C7H7Cl3NO3PS/c1-12-15(16,13-2)14-7-5(9)3-4(8)6(10)11-7/h3H,1-2H3 | |
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Yes |
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Common Name | Relationship | Link |
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chlorpyrifos | Parent | |
chlorpyrifos-methyl | - |
General status |
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Insecticide, Acaricide | |
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Organophosphate insecticide; Organophosphate acaricide; Organothiophosphate insecticide; Organothiophosphate acaricide | |
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960 g kg⁻¹ | |
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EU dossier - Sulfotep <3.0 g kg⁻¹, Sulfotep-ester <5.0 g kg⁻¹ | |
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Synthetic | |
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Non-systemic with contact, stomach and respiratory action. Acetylcholinesterase (AChE) inhibitor. | |
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5598-13-0 | |
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227-011-5 | |
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486 | |
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059102/219300 | |
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21803 | |
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015-084-00-4 | |
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322.53 | |
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O,O-dimethyl O-(3,5,6-trichloropyridin-2-yl) phosphorothioate | |
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O,O-dimethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate | |
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O,O-dimethyl O-(3,5,6-trichloro-2-pyridinyl) phosphorothioate | |
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OSPAR soc; WFD priority substance; Marine Pollutant; PAN Bad Actor Chemical | |
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UK Environment Agency non-statutory standard for the protection of aquatic life: Freshwater annual average 0.002 µg l⁻¹, max acceptable conc 0.01 µg l⁻¹; Saltwater annual average 0.001 µg l⁻¹, max acceptable conc 0.01 µg l⁻¹ | |
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Not applicable | |
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Not applicable | |
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1B | |
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Not applicable | |
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blattella germanica, culex tarsalis, plutella xylostella, sitophilus zeamais, tribolium castaneum, aedes nigromaculis, plus others | |
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White to pale yellow solid with faint characteristic odour | |
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Formulations |
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Usually supplied as an emulsifiable concentrate that is mixed with water and applied as a spray |
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2.74 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low | ||||||||
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250000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Ethyl acetate5 = Verified data used for regulatory purposes |
- | ||||||||
250000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone5 = Verified data used for regulatory purposes |
- | |||||||||
154000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Heptane5 = Verified data used for regulatory purposes |
- | |||||||||
193000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Methanol5 = Verified data used for regulatory purposes |
- | |||||||||
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46 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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Decomposes before boiling | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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175 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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- | - | - | ||||||||
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1.00 X 1004 | Calculated | - | |||||||
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4.00 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
High | ||||||||
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Soluble | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | |||||||
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Regulatory data - observed in metabolism and farm animal feeding studies | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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1.67 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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- | |||||||||||
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3.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Low volatility. If applied directly to plants or soil, drift is a concern & mitigation is advisable | ||||||||
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0.235 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately volatile | ||||||||
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Neutral soln: 203nm=20322, 230nm=10112, 290nm=5449 Acidic soln: 203nm=20367, 230nm=9567, 290nm=5473 Basic soln: 242nm=9475, 290nm=1423, 323nm=6817 |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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71.9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Degradation |
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12.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | |||||||
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12.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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1.24 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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15.4 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | ||||||||
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4.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
- | ||||||||
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1.32 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) geometric mean5 = Verified data used for regulatory purposes |
- | ||||||||
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EU 2017 dossier Lab studies DT₅₀ range 0.83-7.64 days, DT₉₀ range 2.75-38.1 days, Soils=12, Field studies DT₅₀ range 0.62-2.17 days, DT₉₀ range 2.07-7.22 days, Soils=5; Other sources: DT₅₀ 7 days (DW4) | ||||||||||
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2.4 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Bermuda grass leaves, n=1 | ||||||||||
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19.1 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published literature RL₅₀ range 1.0-71.5 days, 4 field crops, various matrices, n=4 | ||||||||||
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1.74 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately fast | |||||||
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21 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-persistent | |||||||
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pH sensitive: 27 days at pH 4, 13 days at pH 9, 25 °C | ||||||||||
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14 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Fast | ||||||||
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2.9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Moderately fast | ||||||||
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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[Wheat grain: 19 wks @ 30 DegC, 50% RH; Modelled data], [Wheat: 17 wks @ 16 Deg C, 13.3 wks @ 23 DegC, 8.6 wks @ 30 DegC, 13% grain moisture; Field study], [Wheat: 41.7 wks @ 16 Deg C, 24.1 wks @ 23 DegC, 12.1 wks @ 30 DegC, 16% grain moisture; Field study], [Corn grain: 27.7 days @ 20-25 DegC, 40-60% RH; Lab study] |
Soil adsorption and mobility |
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- | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Non-mobile | |||||||
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4645 | ||||||||||
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EU dossier Koc range 1189-8100 mL g⁻¹ | ||||||||||
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44.9 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Slightly mobile | |||||||
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1462 | ||||||||||
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0.96 | ||||||||||
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EU 2017 dossier Kf range 25.8-64.5 mL g⁻¹, Kfoc range 691-1892 mL g⁻¹, 1/n range 0.93-0.98, Soils=5 | ||||||||||
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Fate indices |
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0.08 | Calculated | Low leachability | ||||||||||||||||||||||||||
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2.44 X 10-04 | Calculated | - | |||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - | ||||||||||||||||||||||||||
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2.11 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Calculated using the Atkinson method4 = Verified data |
Below the level of concern for long-range air transport | ||||||||||||||||||||||||||
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1800 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
Threshold for concern | |||||||||||||||||||||||||
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2.6 | - |
Known soil metabolites |
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Major fraction | 0.879 | - | |||||
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Minor fraction | 0.049 | - | |||||
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Major fraction | - | - | |||||
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- | - | - |
Known groundwater metabolites |
None
Other known metabolites |
None
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Terrestrial ecotoxicology |
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5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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0.1 | L2 L = Pesticide manuals and hard copy reference books / other sources Rat 2 yr2 = Unverified data of unknown source |
High | |||||||
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923 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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2010 ppm | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Colinus virginianus5 = Verified data used for regulatory purposes |
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182 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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12.5 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Eisenia foetida5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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Nitrogen mineralisation: No significant adverse effect Carbon mineralisation: No significant adverse effect |
A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes Dose: 0.5 kg ha⁻¹ |
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0.075 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Folsomia candida5 = Verified data used for regulatory purposes |
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0.148 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
High | |||||||
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0.177 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
High | ||||||||
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0.002 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Apis mellifera5 = Verified data used for regulatory purposes |
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0.09 | R4 R = Peer reviewed scientific publications Bombus terrestris 48 hr4 = Verified data |
High | |||||||
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> 0.36 | R4 R = Peer reviewed scientific publications Bombus terrestris4 = Verified data |
High | ||||||||
Literature LD₅₀ values range >0.02 - 0.38 µg bee⁻¹ depending on study exposure time | |||||||||||
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9.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Coccinella septempunctata Adults5 = Verified data used for regulatory purposes |
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36.89 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Chrysoperla carnea Larva5 = Verified data used for regulatory purposes |
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0.56 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Aphidius rhopalosiphi Adult5 = Verified data used for regulatory purposes |
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158.25 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Typhlodromus pyri Protonymph5 = Verified data used for regulatory purposes |
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Aquatic ecotoxicology |
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0.41 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
Moderate | ||||||||
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0.005 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Oncorhynchus mykiss5 = Verified data used for regulatory purposes |
High | ||||||||
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9.88 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents / FAO data, IPCS INCHEM data (US EPA Databases Related to Pesticide Risk Assessment ) Danio rerio EC₅₀ Embryo3 = Unverified data of known source |
Moderate | ||||||||
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0.0006 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.00001 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Daphnia magna5 = Verified data used for regulatory purposes |
High | ||||||||
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0.57 | L2 L = Pesticide manuals and hard copy reference books / other sources Raphidocelis subcapitata2 = Unverified data of unknown source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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5000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
Low | ||||||||
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2000 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat5 = Verified data used for regulatory purposes |
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> 0.67 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Rat (whole body)5 = Verified data used for regulatory purposes |
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None allocated | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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None allocated | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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None allocated | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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List I; List II | - | - | ||||||||
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Absorbed from the gastrointestinal tract and through intact skin | ||||||||||
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Non-statutory WHO drinking water guideline 0.03 mg l⁻¹ | B5 B = UK CRD and ACP Evaluation Documents / and other DEFRA (UK) documents; Also Chemicals Regulation Division, Health and Safety Executive (HSE), UK (click here ) UK EA QS database 20185 = Verified data used for regulatory purposes |
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Extensively metabolised, and eliminated maily via the urine within 72 hrs | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Health issues |
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Suspected cardiovascular & blood toxicant Highly toxic by ingestion Some studies indicate a link between chlorpyrifos metabolites and learning difficulties in children Endocrine issues - Antagonist to androgen activity |
Handling issues |
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Not explosive or oxidising IMDG Transport Hazard Class 6.1 Not expected to auto-ignite; Not highly flammable |
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Health: H317 Environment: H400, H410 |
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III (Slightly hazardous) | |||
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UN2811 | |||
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Packaging Group III (minor danger) | |||
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chlorpyrifos-methyl | ||
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chlorpyriphos-methyl | ||
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Chlorpyrifos-methyl | ||
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chlorpyrifos-methyl | ||
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clorpirifos-metile | ||
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clorpirifos-metil | ||
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chlorpyrifos-methyl | ||
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chloropyrifos metylowy | ||
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klorpirosz-metil | ||
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chloorpyrifos-methyl | ||
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Record last updated: | 23/08/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |