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dichlorvos (Ref: OMS 14)
** DDVP ** dichlorfos ** DDVF ** denkavepon ** vapona ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Dichlorvos is an organophosphate fumigant insecticide that is not approved for use in the EU. It has a high aqueous solubility, quite volatile and, based on its chemical properties, is unlikely to leach to groundwater. It is not usually persistent in soils or water. It is highly toxic to mammals and has a high tendency to bioaccumulate. Dichlorvos is also a probable mutagen, a neurotoxin and may damage reproduction and/or development. It is considered to be an acetyl cholinesterase inhibitor. It has a moderate to high toxicity to most biodiversity including honeybees.

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for dichlorvos

Description: A contact and fumigant insecticide used in a range of crop and non-crop situations. Can also be a pesticide transformation product

Example pests controlled: Grain beetle; Flour beetle; Weevils; Grain borer; Flies; Mosquitoes; Cockroaches; Aphids; Thrips

Example applications: Stored cereal grains; Farm buildings; Non-agricultural sites including wineries, factories

Efficacy & activity: Not applicable

Availability status: Current

Introduction & key dates: 1959

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Italy
Date inclusion expires Expired
EU Candidate for substitution (CfS) -
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism None
Chemical formula C4H7C12O4P
Canonical SMILES COP(=O)(OC)OC=C(Cl)Cl
Isomeric SMILES O=P(O\C=C(/Cl)Cl)(OC)OC
International Chemical Identifier key (InChIKey) OEBRKCOSUFCWJD-UHFFFAOYSA-N
International Chemical Identifier (InChI) InChI=1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Insecticide, Acaricide, Metabolite
Metabolite Type Soil
Substance group Organophosphate
Minimum active substance purity 950 g/kg
Known relevant impurities EU dossier - Chloral (trichloroacetaldehyde) 5 g/kg
Substance origin Synthetic
Mode of action Respiratory, contact and stomach action. Cholinesterase inhibitor.
CAS RN 62-73-7
EC number 200-547-7
CIPAC number 11
US EPA chemical code 084001
PubChem CID 3039
Molecular mass (g mol-1) 220.98
PIN (Preferred Identification Name) 2,2-dichloroethenyl dimethyl phosphate
IUPAC name 2,2-dichlorovinyl dimethyl phosphate
CAS name 2,2-dichloroethenyl dimethyl phosphate
Other status information Severe Marine Pollutant; Evidence of use in third world countries; Chemical subject to PIC regulations
Relevant Environmental Water Quality Standards UK Statutory standard for the protection of aquatic life in inland waters: 0.001 ug/L as annual average
UK Statutory standard for the protection of aquatic life in coastal and territorial waters: 0.04 ug/L as annual average
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Aphis gossypii
Culex pipiens pallens
Frankliniella occidentalis
Musca domestica
Myzus persicae
Thrips tabaci
Tribolium confusum
many others
Physical state Pale yellow clear liquid
Related substances & organisms -

Can be a metabolite of:
Parent Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
naled Soil   0.165   -
trichlorfon Soil   0.245   Major fraction, Relevant

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Value Garden Supplies
  • Fuller Systems
  • Nufarm
  • Ciba Geigy
  • Nippon Soda
  • KenoGard
Example products using this active
  • Dichlorvos 550
  • Derribante
  • Valpona
  • Derriban
  • Vaportape
  • Dichlorvos 1140
UK LERAP status No UK approval for use as a pesticide under EC Regulation 1107/2009
Formulation and application details Often supplied as an emulsifiable concentrate that is diluted with water and used with fogging vaporising equipment. Also used as ready-to-use aerosols.


ENVIRONMENTAL FATE

for dichlorvos

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 18000 A5 High
Solubility - In organic solvents at 20oC (mg l-1) Miscible A5 - Ethanol -
Miscible A5 - Acetone -
Miscible A5 - Toluene -
Miscible A5 - n-Hexane -
Melting point (oC) - - -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 190 A5 -
Flashpoint (oC) 350 V3 -
Octanol-water partition coefficient at pH 7, 20oC P 7.94 X 1001 Calculated -
Log P 1.9 A5 Low
Bulk density (g ml-1)/Specific gravity 1.42 A5 -
Dissociation constant (pKa) at 25oC Not applicable Q3 -
Note: No dissociation
Vapour pressure at 20oC (mPa) 2100 A5 Highly volatile
Henry's law constant at 25oC (Pa m3 mol-1) 2.58 X 10-02 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index 0.69 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.60 X 10-03 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Maxima at 204nm A2 -
Surface tension (mN m-1) - - -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 2 K4 Non-persistent
DT50 (lab at 20oC) 2 K4 Non-persistent
DT50 (field) - - -
DT90 (lab at 20oC) - - -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note Other sources: DT50 0.5 days (DW4), <1 day (R3)
Dissipation rate RL50 on plant matrix Value 0.2 R3 -
Note Chrysanthmum leaves, undercover, n=1
Dissipation rate RL50 on and in plant matrix Value 1.9 R4 -
Note Published literature RL50 range 0.2-3.5 days, 5 field crops, various matrices, n=5
Aqueous photolysis DT50 (days) at pH 7 Value - - -
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 4.7 K3 Non-persistent
Note -
Water-sediment DT50 (days) 0.22 K4 Fast
Water phase only DT50 (days) - - -

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - H3 Mobile
Koc 50
Notes and range -
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
mercapturic acid - Rat (Urinary) - -
methyl cystein - Rat (Urinary) - -
urea - Rat (Urinary) - -
diemethyl dichlorvos
Note: Toxicologically relevant
- Rat - -
2,2-dichloroacetaldehyde
Note: Toxicologically relevant
- Rat - -
2,2-dichloroacetic acid
Note: Toxicologically relevant
- Rat - -
dimethylphosphate - Rat (Urinary) - -
dichloroethanol glucuronide - Rat (Urinary) - -
hippuric acid - Rat (Urinary) - -


ECOTOXICOLOGY

for dichlorvos

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) 80 A5 Rat High
Mammals - Short term dietary NOEL (mg kg-1) 0.5 A5 Rat High
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) 24 L3 Colinus virginianus High
Birds - Short term dietary (LC50/LD50) 251 ppm A4 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) 0.55 A5 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) 0.11 Q2 Pimephales promelas, 28 day Moderate
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.00019 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.019 F4 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) 52.8 L3 Scenedemus subspicatus Low
Algae - Chronic 96 hour NOEC, growth (mg l-1) 4.73 Q2 Unknown species Low
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) 0.29 L3 High
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) - - -
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect - - -
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 13.4 mg kg-1 soil
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for dichlorvos

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 80 A5 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 120 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.083 A5 Rat -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.00008 A5 Dog, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.002 A5 Rat, SF=100 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.0005 A2 Dog, SF=100 -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Routes Public Low risk to Europeans as no longer approved for use
Occupational Primary risk if re-entry occurs post application
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A2; B2; C2; D2; E1

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues IARC Group 2B carcinogen
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin
Some minor concerns regarding endocrine disruption
Endocrine issues - Weak androgen-receptor antagonist
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Corrosive in molten state
IMDG Transport Code is usually 6.1
CLP classification 2013 Health: H301, H311, H317, H330
Environment: H400
EC Risk Classification Click here to view information omn the EU risk phrases T+ - Very toxic: R26
T - Toxic: R24/25
Xn - Harmful: R43
N - Dangerous for the environment: R50
EC Safety Classification Click here to view information omn the EU safety phrases S1/2, S28, S36/37, S45, S61
WHO Classification Ib - Highly hazardous
UN Number 3018
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group II (medium danger)


TRANSLATIONS

for dichlorvos

Language Name
English dichlorvos
French dichlorvos
German Dichlorvos
Danish dichlorvos
Italian diclorvos
Spanish diclorvos
Greek dichlorvos
Slovenian diklorvos
Polish dichlorfos
Swedish -
Hungarian dichlorvos
Dutch dichloorvos

Record last updated: Tuesday 25 June 2019
Contact: aeru@herts.ac.uk