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fosetyl-aluminium (Ref: RP 32545)
** fosetyl ** efosite-Al ** EPAL ** aluminium phosethyl ** LS 74783 ** fosetyl-Al ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

SUMMARY

Fosetyl aluminium is an approved fungicide under EU regulations. It has a high aqueous solubility and a low volatility. It is not usually persistent in soil systems but may, under certain conditions, persist in water. It has a low mammalian toxicity and is not associated with any serious medical conditions but may be an eye irritant. It has a low to moderate toxicity to most terrestrial and aqueous species

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for fosetyl-aluminium

Description: A fungicide for various horticultural crops used to control a range of plant pathogens.

Example pests controlled: Phytophthora and Pythium root and crown rots, Pseudomonas apple blister spot, Alternaria

Example applications: Fruit including grapes, apples, pears, raspberry, blackberry, strawberry; Ginseng; Lettuce; Onion; Broccoli; Tobacco; Turf; Ornamentals

Efficacy & activity: The substance has been extensively evaluated in field trials across a wide range of EU Member States which have confirmed its effectiveness.

Availability status: Current

Introduction & key dates: 1977, first reported & first registered France

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur France/Estonia
Date inclusion expires 30/04/2020
EU Candidate for substitution (CfS) No
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia, USA

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism Fosetyl is a chiral molecule
Chemical formula C6H18AlO9P3
Canonical SMILES CCOP(=O)=O.CCOP(=O)=O.CCOP(=O)=O.[Al+3]
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) ZKZMJOFIHHZSRW-UHFFFAOYSA-K
International Chemical Identifier (InChI) InChI=1S/3C2H7O3P.Al/c3*1-2-5-6(3)4;/h3*6H,2H2,1H3,(H,3,4);/q;;;+3/p-3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Fungicide, Bactericide
Substance group Organophosphate
Minimum active substance purity 960 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Systemic, absorbed through leaves and roots
CAS RN 39148-24-8
EC number 254-320-2
CIPAC number 384.013
US EPA chemical code 123301
PubChem CID 6328269
Molecular mass (g mol-1) 354.10
PIN (Preferred Identification Name) -
IUPAC name aluminium tris(ethyl phosphonate)
CAS name aluminium tris-O-ethylphosphonate
Other status information Potential groundwater contaminant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) Not applicable
Herbicide Resistance Classification (WSSA) Not applicable
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) 33
Examples of recorded resistance -
Physical state White powder
Related substances & organisms

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Certis
  • Standon
  • FCC
  • King Tech Corp
Example products using this active
  • Aliette 80 WG
  • Fullstop
  • Pilarfarm
  • Chipco aliette WDG
UK LERAP status None
Formulation and application details Often supplied as wettable granules or a wettable powder that are mixed with water and applied as a foliar spray or used as a seed treatment.


ENVIRONMENTAL FATE

for fosetyl-aluminium

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 111300 A5 High
Solubility - In organic solvents at 20oC (mg l-1) 1 A5 - n-Heptane -
6 A5 - Acetone -
1 A5 - Xylene -
807 A5 - Methanol -
Melting point (oC) 215 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 277 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 7.94 X 10-03 Calculated -
Log P -2.1 A5 Low
Bulk density (g ml-1)/Specific gravity 1.53 A5 -
Dissociation constant (pKa) at 25oC 4.7 A5 -
Note: Weak acid
Vapour pressure at 20oC (mPa) 1.00 X 10-04 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 3.20 X 10-10 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index - - -
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value - - -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 No UV absorption from 190-800nm A5 -
Surface tension (mN m-1) 75.1 A5 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 0.018 Click here to see a warning relating to modelling and this active substance A5 Non-persistent
DT50 (lab at 20oC) 0.018 A5 Non-persistent
DT50 (field) 0.04 H4 Non-persistent
DT90 (lab at 20oC) 0.11 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU 2017 dossier Lab studies DT50 range 0.005-0.04 days, DT90 range 0.03-0.2, Soils = 6; Other sources: DT50 1.0 days (DW4)
Dissipation rate RL50 on plant matrix Value - - -
Note -
Dissipation rate RL50 on and in plant matrix Value - - -
Note -
Aqueous photolysis DT50 (days) at pH 7 Value 35 A5 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value Stable A5 -
Note Stable pH 5 to pH 9
Water-sediment DT50 (days) 3.0 A5 Fast
Water phase only DT50 (days) 1.22 A5 Moderately fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - A5 -
Koc -
Notes and range Not adsorbed
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range Low absorption
pH sensitivity None

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
ethanol Soil, Groundwater   -   Not relevant
phosphonic acid This metabolite may cause environmental pollution, click here for further information Soil   1.00   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
Phosphorous acid
Note: Rat oral LD50 3624 mg kg-1 bw
H3PO3 Plant; Soil - -


ECOTOXICOLOGY

for fosetyl-aluminium

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) Low risk A5 Based on LogP < 3 Low potential
CT50 (days) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Short term dietary NOEL (mg kg-1) > 1424 A5 Rat Moderate
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 8000 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 20000 mg kg feed-1 A5 Colinus virginianus -
Fish - Acute 96 hour LC50 (mg l-1) > 122 A5 Oncorhynchus mykiss Low
Fish - Chronic 21 day NOEC (mg l-1) > 100 A5 Oncorhynchus mykiss Low
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 100 A5 Daphnia magna Low
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) 17 A5 Daphnia magna Low
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 79.7 A5 Lemna gibba Low
Non-target plants > 80 A5 6 plant species
Vegetative vigour, ER50
as g/ha
-
> 7 A5 Oilseed rape
Seedling emergence, ER50
as g/ha
-
Algae - Acute 72 hour EC50, growth (mg l-1) 5.9 A5 Scenedesmus acutus Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) 1 Q2 Unknown species Moderate
Honeybees Contact acute 48 hour LD50 (μg bee-1) > 100 A5 Apis mellifera Low
Oral acute 48 hour LD50 (μg bee-1) 462 A5 Apis mellifera Low
Unknown mode acute 48 hour LD50 (μg bee-1) - - -
Earthworms - Acute 14 day LC50 (mg kg-1) > 1000 A5 Eisenia foetida Low
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) 316 A5 Eisenia foetida Low
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 64000 >, 48 hour
A5 Aphidius rhopalosiphi, adult
-
% Effect 30.2 Mortality
Parasitism
Dose: 5 kg ha-1
A5 Aphidius rhopalosiphi
-
Other arthropod (2) LR50 g ha-1 - - -
% Effect 86.7
100
Mortality
Reproduction
Dose: 18.56 kg ha-1
A5 Typhlodromus pyri
-
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 20 kg ha-1
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for fosetyl-aluminium

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) > 2000 A5 Rat Low
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 5.11 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 3.0 A5 SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) None allocated A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) 1.0 A5 Rabbit, SF=100 -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 5.0 A5 Rat, 90 day, SF=100 -
Dermal penetration studies (%) 1.0 A5 -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public Negligible risk to bystanders
Occupational Negligible risk of operator and other worker exposure but occupational exposure may occur through inhalation and dermal contact. PPE/PPC recommended
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; Calc MAC=8940 μg l-1; A5 -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

General human health issues May cause nausea, vomiting and diarrhea if ingested
May cause cough, tachypnea and wheezing if inhaled

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not explosive or oxidising
IMDG Transport Code is 6.1
CLP classification 2013 Health: H318, H319
EC Risk Classification Click here to view information omn the EU risk phrases Xn- Harmful: R41
EC Safety Classification Click here to view information omn the EU safety phrases S2, S26, S39, S46
WHO Classification U - Unlikely to present an acute hazard
US EPA Classification (formulation) III - Caution - Slightly toxic
UN Number Active 2783, liquid products usually 3018
Waste disposal & packaging Click here for a description of UN packaging marks -


TRANSLATIONS

for fosetyl-aluminium

Language Name
English fosetyl-aluminium
French forsetyl-al
German Fosetyl-Al
Danish fosetyl-al
Italian fosetil-alluminio
Spanish fosetil-Al
Greek -
Slovenian fosetil-aluminij
Polish fosetyl glinowy
Swedish fosetylaluminium
Hungarian fosetil-al
Dutch fosetyl-aluminium

Record last updated: Wednesday 03 April 2019
Contact: aeru@herts.ac.uk