Azinphos-ethyl (Ref: BAY 16259)
Last updated: 04/03/2022
(Also known as: azinphosethyl; triazotion; azinphos ethyl; R1513; ethyl gusathion)
Azinphos-ethyl is an organophosphate insecticide used to control sucking and chewing pests. It has a low aqueous solubility, relatively volatile and is not expected to leach to groundwater. It may be moderately persistent in some soil systems but is not expected to be persistent in water. It is toxic to mammals and there is also concern regarding its potential to bioaccumulate. It is a neurotoxicant and an acetyl cholinesterase inhibitor. Azinphos-ethyl is highly toxic to birds, fish and aquatic invertebrates. It is moderately toxic to honeybees.
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A benzotriazine organothiophosphate insecticide and organothiophosphate acaricide for the control of sucking and chewing pests
Spider mites; Aphids; Caterpillers; Potato bugs including Colorado beetles; Oat mites; Tocks
Cotton; Rice; Tobacco; Melons; Tomatoes; Potatoes; Hops; Beet crops; Citrus; Soybeans; Apples
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-
1955
Not approved
Expired
No UK approval for use
EC Regulation 1107/2009 (repealing 91/414)
Not approved
Germany
Expired
-
Yes
ATAustria
BEBelgium
BGBulgaria
CYCyprus
CZCzech Republic
DEGermany
DKDenmark
EEEstonia
ELGreece
 
 
 
 
 
 
 
 
 
ESSpain
FIFinland
FRFrance
HRCroatia
HUHungary
IEIreland
ITItaly
LTLithuania
LULuxembourg
 
 
 
 
 
 
 
 
 
LVLatvia
MTMalta
NLNetherlands
PLPoland
PTPortugal
RORomania
SESweden
SISlovenia
SKSlovakia
 
 
 
 
 
 
 
 
 
None
C₁₂H₁₆N₃O₃PS₂
CCOP(=S)(OCC)SCN1C(=O)C2=CC=CC=C2N=N1
No data
RQVGAIADHNPSME-UHFFFAOYSA-N
InChI=1S/C12H16N3O3PS2/c1-3-17-19(20,18-4-2)21-9-15-12(16)10-7-5-6-8-11(10)13-14-15/h5-8H,3-4,9H2,1-2H3
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
azinphos-ethyl
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Insecticide, Acaricide
Organophosphate Insecticide; Organophosphate acaricide; Organothiophosphate insecticide; Organothiophosphate acaricide
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Synthetic
Non-systemic, contact and stomach action. Cholinesterase inhibitor. Ovicidal.
2642-71-9
220-147-6
485
058002
17531
345.38
O,O-diethyl S-[(4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl] phosphorodithioate
S-3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl O,O-diethyl phosphorodithioate
O,O-diethyl S-((4-oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorodithioate
Severe Marine Pollutant; Chemical subject to PIC regulations; PAN Bad Actor Chemical; Subject to the provisions of the UK Poisons Act 1972
-
Not applicable
Not applicable
1B
Not applicable
Culex pipiens pipiens , Myzus persicae , Phorodon humuli
Colourless needle-like crystals
Gusthion A Gusthion H Cotnion-ethyl Guthion M-E 4 Concentrate
Available in a variety of formulations including dusts, emulsifiable concentrates, ULVs and wettable powders.
4.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low
3500
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
n-Hexane
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35000
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Isopropanol
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1000000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Dichloromethane
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1000000
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Toluene
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50
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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111
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-
-
-
-
-
-
1.51 X 1003
Calculated
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3.18
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
High
1.28
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
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-
-
-
-
0.32
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Low volatility
3.05 X 10-06
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Non-volatile
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-
-
-
-
-
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50
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Moderately persistent
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-
-
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-
-
-
-
-
-
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Best available data
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10
R4 R = Peer reviewed scientific publications 4 = Verified data
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Apple fruit, n=1; Apples in store RL₅₀ range 83-91 days, n=2
0.4
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Fast
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13
K4 K = Research datasets, e.g. Pandora, Demetra 4 = Verified data
Non-persistent
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-
-
-
-
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-
Soil adsorption and mobility
-
P2 P = Other governments and regulators 2 = Unverified data of unknown source
Slightly mobile
1500
Other source Koc 1700 mL g⁻¹ estimate (CA2)
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-
-
-
-
-
-
1.40
Calculated
Low leachability
3.46 X 10-02
Calculated
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-
High
Calculated
-
Slightly mobile
Calculated
-
101
Q2 Q = Miscellaneous internet resources 2 = Unverified data of unknown source
Estimated
Threshold for concern
Not available
-
Terrestrial ecotoxicology
12
Rat
High
-
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 2 year
-
2
-
-
-
-
> 12.5
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Coturnix japonica
High
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
> 1.39
R4 R = Peer reviewed scientific publications 4 = Verified data
Moderate
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
0.08
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Oncorhynchus mykiss
High
-
-
-
0.0002
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Daphnia magna
High
-
-
-
-
-
-
-
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-
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-
-
-
-
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HUMAN HEALTH AND PROTECTION
High (class III)
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-
12
Rat
High
500
L2 L = Pesticide manuals and hard copy reference books / other sources 2 = Unverified data of unknown source
Rat 24hr
-
0.15
L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source
Rat
-
-
-
-
0.03
Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source
as ug/day India
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-
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List I; List II
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Consumer exposure should be low or non-existent since azinphos ethyl is no longer produced or used in most of the developed world
Occupational exposure should be low or non-existent since azinphos ethyl is no longer produced or used in most of the developed world
EU MRL pesticide database 
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A3 A = Chromosome aberration (EFSA database) 3 = Negative
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E0 E = Unspecified genotoxicity type (miscellaneous data source) 0 = No data
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
XNo, known not to cause a problem
✓Yes, known to cause a problem
✓Yes, known to cause a problem
Respiratory tract irritant
Skin irritant
Skin sensitiser
XNo, known not to cause a problem
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
No further information available
IMDG Transport Code is 6.1 Not expected to autoignite; Not highly flammable
Health: H300, H311 Environment: H400, H410
Ib (Highly hazardous)
Active 2783, liquid products usually 3018
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azinphos-ethyl
azinphos-ethyl
Azinphos-ethyl
azinphos-ethyl
azinfos-etile
azinfos-etil
azinphos-ethyl
azinofos etylowy
-
azinphos-ethyl
azinfos-ethyl
Record last updated:
04/03/2022
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242