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quizalofop-P-tefuryl (Ref: UBI C4874 )
** pantera ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION Click here for an explantaion of the general chemical status information
for quizalofop-P-tefuryl

Description: A herbicide for the control of annual grass and broad-leaved weeds in a variety of crops

Example pests controlled: Bentgrass; Volunteer cereals; Perennial ryegrass; Italian ryegrass; Couch

Example applications: Sugarbeet; Fodder beet; Winter and spring OSR; Potatoes; Combining peas; Field beans; Other pulses; Linseed; Sunflowers

Efficacy & activity: -

Availability status: Current

Introduction & key dates: 1989

EC Regulation 1107/2009 (repealing 91/414):
Status Approved
Dossier rapporteur/co-rapporteur Hungary/UK
Date inclusion expires 30/11/2021
EU Candidate for substitution (CfS) Yes - toxic for reproduction
Listed in EU database Yes

Approved for use () or known to be used () in the following European countries: Click to access a note on the approvals information on this site

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

Also used in: Australia

Chemical structure: Click here for further information on the general chemical status information used on this site
Isomerism A chiral molecule. Quizalofop-P-tefuryl is the more biologically active enantimer of the racemate quizalofop-tefuryl.
Chemical formula C22H21CIN2O5
Canonical SMILES CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl
Isomeric SMILES No data
International Chemical Identifier key (InChIKey) BBKDWPHJZANJGB-IKJXHCRLSA-N
International Chemical Identifier (InChI) InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3
2D structure diagram/image available? Yes

General status: Click here for further information on the general chemical status information used on this site
Pesticide type Herbicide
Substance group Aryloxyphenoxypropionate
Minimum active substance purity 926 g/kg
Known relevant impurities EU dossier - None declared
Substance origin Synthetic
Mode of action Systemic, absorbed through leaves and translocated. An acetyl CoA carboxylase inhibitor (ACCase).
CAS RN 119738-06-6
EC number 414-200-4 (601-628-3)
CIPAC number -
US EPA chemical code -
PubChem CID 86175
Molecular mass (g mol-1) 428.89
PIN (Preferred Identification Name) [(2E)-oxolan-2-yl]methyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate
IUPAC name (RS)-tetrahydrofurfuryl (R)-2-[4-(6-chloroquinoxalin-2-yloxy)phenoxy]propionate
CAS name (tetrahydro-2-furanyl)methyl (2R)-2-(4-((6-chloro-2-quinoxalinyl)oxy)phenoxy)propanoate
Other status information Severe Marine Pollutant
Relevant Environmental Water Quality Standards -
Herbicide Resistance Classification (HRAC) A
Herbicide Resistance Classification (WSSA) 1
Insecticide Resistance Classification (IRAC) Not applicable
Fungicide Resistance Classification (FRAC) Not applicable
Examples of recorded resistance Echinochloa crus-galli
Sorghum sudanese
Physical state Technical materrial is a thick yellow liquid
Related substances & organisms -

Formulations:
Property Click here for information on the general product and branding information used on this site Value
Example manufacturers & suppliers of products using this active now or historically
  • Certis
  • Crompton Specialties
Example products using this active
  • Panarex
  • Pantera
UK LERAP status None
Formulation and application details Often supplied as an emulsifiable concentrate that is mixed with water and used as a spray.


ENVIRONMENTAL FATE

for quizalofop-P-tefuryl

Property Click here for information on the parameters used to describe environmental fate on this site Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with fate data Interpretation Click here for information on the way in which we interpret environmental fate data
Solubility - In water at 20oC (mg l-1) 3.13 A4 - at 25 DegC Low
Solubility - In organic solvents at 20oC (mg l-1) 652000 A5 - Toluene -
12000 A5 - Hexane -
64000 A5 - Methanol -
221000 A5 - Acetone -
Melting point (oC) 58.3 A5 -
Boiling point (oC) Decomposes before boiling A5 -
Degradation point (oC) 211 A5 -
Flashpoint (oC) Not expected to self ignite; Not highly flammable A5 -
Octanol-water partition coefficient at pH 7, 20oC P 2.09 X 1004 Calculated -
Log P 4.32 A5 High
Bulk density (g ml-1)/Specific gravity 1.28 L3 -
Dissociation constant (pKa) at 25oC -1.25 A5 -
Note: Strong acid, 25 DegC
Vapour pressure at 20oC (mPa) 7.90 X 10-03 A5 Low volatility
Henry's law constant at 25oC (Pa m3 mol-1) 9.0 X 10-04 A5 Non-volatile
GUS leaching potential index Click here for a note on the limitations of the GUS index -0.24 Calculated Low leachability
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Click here for a note on the limitations of the SCI-GROW index Value 1.38 X 10-04 Calculated -
Note -
Potential for particle bound transport index Click here for a note on the limitations of the potential for particle bound transport index - Calculated Low
Maximum UV-vis absorption L mol-1 cm-1 Neutral solution 238nm = 15171; [Acidic solution 238 nm = 15169; [Basic solution 238 nm= 15081 A5 -
Surface tension (mN m-1) 69.3 A5 at 20oC, 1.73 mg l-1 -

Degradation:
Property Click here for information on the parameters used to describe substance degradation Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with degradation data Interpretation Click here for information on the way in which we interpret substance degradation data
General biodegradability -
Soil degradation (days) (aerobic) DT50 (typical) 0.2 Click here to see a warning relating to modelling and this active substance L3 Non-persistent
DT50 (lab at 20oC) 0.16 A5 Non-persistent
DT50 (field) 0.66 A2 Non-persistent
DT90 (lab at 20oC) 0.88 A5 -
DT90 (field) - - -
DT50 modelling endpoint - - -
Note EU dossier lab studies DT50 range 0.04-0.62 days, DT90 range 0.2-3.1 days; field studies DT50 range 0.5-2.5 days [From DAR]
Dissipation rate RL50 on plant matrix Value 0.6 R3 -
Note Mung bean, whole plant, n=1
Dissipation rate RL50 on and in plant matrix Value 3.1 R4 -
Note Published literature RL50 range 0.7-5.6 days, 2 field grown crops, various matrices, n=2
Aqueous photolysis DT50 (days) at pH 7 Value 1.0 A5 Moderately fast
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 18.2 A5 Non-persistent
Note pH sensitive: DT50 8.2 days at pH 5.1, 7.2 hours at pH 9.2, all at 22 degC
Water-sediment DT50 (days) 0.08 A5 Fast
Water phase only DT50 (days) 0.11 A5 Fast

Soil adsorption and mobility:
Property Click here for information on the parameters used to describe substance adsorption and mobility Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with adsorption and mobility data Interpretation Click here for information on the way in which we interpret substance adsorption and mobility
Linear Kd - L3 Moderately mobile
Koc 477
Notes and range EU dossier - substance degrades rapidly in aerobic soils to the acid.
Freundlich Kf - - -
Kfoc -
1/n -
Notes and range -
pH sensitivity -

Key metabolites:
Metabolite Formation medium Estimated maximum occurrence fraction 1107/2009 relevancy Click here for further information on 1107/2009 relevancy
quizalofop (Ref: CGA 287422) This metabolite may cause environmental pollution, click here for further information Soil   1.00   Major fraction, Relevant
hydroxy quizalofop (Ref: CGA 294972) This metabolite may cause environmental pollution, click here for further information Soil   0.21   Major fraction, Relevant
dihydroxy quinoxaline (Ref: CGA 294970) This metabolite may cause environmental pollution, click here for further information Soil   0.180   Major fraction, Relevant

Other known metabolites:
Metabolite name and reference Aliases Formation medium / Rate Estimated maximum occurrence fraction Metabolising enzymes
hydroxy-quinoxaline CHQ Soil 0.058 -
tetrahydrofurfuryl alcohol - Soil - -
tetrahydrofuroic acid - Soil - -


ECOTOXICOLOGY

for quizalofop-P-tefuryl

Property Click here for information on the parameters used to describe substance ecotoxicology Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with ecotoxicology data Interpretation Click here for information on the way in which we interpret substance ecotoxicology
Bio-concentration factor BCF (l kg-1) 340 A5 Whole fish Threshold for concern
CT50 (days) 0.9 -
Mammals - Acute oral LD50 (mg kg-1) 1012 A5 Rat Moderate
Mammals - Short term dietary NOEL (mg kg-1) > 125 L3 Rat Moderate
(ppm diet) - -
Birds - Acute LD50 (mg kg-1) > 2150 A5 Colinus virginianus Low
Birds - Short term dietary (LC50/LD50) > 258.6 mg kg bw-1 day-1 A5 Anas platyrhynchos -
Fish - Acute 96 hour LC50 (mg l-1) 0.23 A5 Lepomis macrochirus Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) > 1.51 A5 Daphnia magna Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) 2.1 A5 Lemna gibba Moderate
Non-target plants - - -
- - -
Algae - Acute 72 hour EC50, growth (mg l-1) > 1.9 A5 Pseudokirchneriella subcapitata Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees (Apis spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 100 A5 Apis mellifera Low
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) > 100 A5 Apis mellifera Low
Unknown mode acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Bumblebees (Bombus spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
-
Mason bees (Osmia spp.) Contact acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Oral acute LD50 (worst case from 24 , 48 and 72 hour values - μg bee-1) - - -
Other pollinators (1) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Other pollinators (2) Acute LD50 (worst case from 24 , 48 and 72 hour values - μg insect-1) - - -
Mode of exposure -
Earthworms - Acute 14 day LC50 (mg kg-1) > 500 A5 Eisenia foetida, corr Moderate
Earthworms - Chronic NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms Acute LC50 (mg kg-1) - - -
Chronic NOEC (mg kg-1) - - -
Other arthropod (1) LR50 g ha-1 100 <, Mortality
A5 Typhlodromus pyri
-
% Effect - - -
Other arthropod (2) LR50 g ha-1 100 <, Mortality
A5 Aphidius rhopalosiphi
-
% Effect - - -
Soil micro-organisms Nitrogen mineralisation: No significant adverse effect
Carbon mineralisation: No significant adverse effect
A5
Dose: 0.133 mg kg-1 soil, 28 days
-
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for quizalofop-P-tefuryl

General:
Property Click here for information on the parameters used to describe human health and protection issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with human health and protection data Interpretation Click here for information on the way in which we interpret human health and protection data
Threshold of Toxicological Concern (Cramer Class) Click here for a note on the limitations of the Cramer class High (class III) - -
Mammals - Acute oral LD50 (mg kg-1) 1012 A5 Rat Moderate
Mammals - Dermal LD50 (mg kg-1 body weight) > 2000 A5 Rat -
Mammals - Inhalation LC50 (mg l-1) > 3.9 A5 Rat, 4 hr (nose only) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.013 A5 Rat, SF=100 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) 0.1 A5 -
AAOEL - Acute Acceptable Operator Exposure Level (mg kg-1 bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) 0.01 A5 Rat, SF=100 -
Dermal penetration studies (%) 18-28 A5 concentration dependent -
Dangerous Substances Directive 76/464 - - -
Exposure Routes Public Negligible risk to bystanders
Occupational Operators should use PPE
Negligible risk to other works for proposed conditions of use
European MRLs Click here for the EU MRL pesticide database
Drinking Water Standards - - -
Drinking Water MAC (μg l-1) 0.1 EU Dir 89/778/EC limit; A5 -

Health issues:
Carcinogen Genotoxic Endocrine disrupter Reproduction / development effects Cholinesterase inhibitor Neurotoxicant

A3; B3; C3; D0; E2

-

-

Respiratory tract irritant Skin irritant Skin sensitiser Eye irritant Phototoxicant

-

-

General human health issues Moderately toxic
Liver toxicant
Key: Genotoxicity
A: Chromosome aberration (EFSA database)
B: DNA damage/repair (EFSA database)
C: Gene mutation (EFSA database)
D: Genome mutation (EFSA database)
E: Unspecified genotoxicity type (miscellaneous data source)
0: No data
1: Positive
2: Mixed/ambiguous results
3: Negative
Key: Other
: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data found

Handling issues:
Property Click here for information on the parameters used to describe substance handling issues Value Source/Quality Score/Other Information Click here for information on the primary data sources used to populate this database with data on handling issues Interpretation Click here for information on the way in which we interpret data on handling issues
General Click here for a description of the International Maritime Dangerous Goods (IMDG) codes Not flammable, explosive or oxidising
IMDG Transport Code is usually 9
CLP classification 2013 Health: H302, H341, H360, H373
Environment: H400, H411
EC Risk Classification Click here to view information omn the EU risk phrases Reproduction risk category 2 and 3: R61, R62
T - Toxic: R68
Xn - Harmful: R48/22, R22
N - Dangerous for the environment: R50, R53
EC Safety Classification Click here to view information omn the EU safety phrases S45, S53, S60, S61
WHO Classification II - Moderately hazardous
UN Number Usually 3082
Waste disposal & packaging Click here for a description of UN packaging marks Packaging Group III (minor danger)


TRANSLATIONS

for quizalofop-P-tefuryl

Language Name
English quizalofop-P-tefuryl
French quizalofop-P-tefuryl
German Quizalofop-P-tefuryl
Danish quizalofop-P-tefuryl
Italian quizalofop-P-tefuryl
Spanish quizalofop-P-teruril
Greek -
Slovenian kvizalofop-P-tefuril
Polish kwizalofop-P-tefurylowy
Swedish -
Hungarian quinzalofop-P-tefuril
Dutch -

Record last updated: Monday 11 November 2019
Contact: aeru@herts.ac.uk