Alpha-endosulfan |
![]() Last updated: 16/12/2020 |
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(Also known as: endosulfan I) |
SUMMARY |
Alpha-endosulfan is an insecticide that is not generally approved for use in the developed world. It has some potential for bio-concentration, highly toxic to mammals and a neurotoxin. Alpha-endosulfan has a low aqueous solubility and moderately. It is moderately persistent in the soil but has a low mobility. It is moderately toxic to birds and most aquatic species. |
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An insecticide and acaricide used to control sucking, chewing and boring insects | |
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Mites; Ticks; Tstetse fly; Colorado beetle; Aphids; White flies; Leaf hoppers | |
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Cotton; Potatoes; Tomatoes; Apples | |
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Unknown | |
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circa 1956 |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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No | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Chemical structure |
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This is one of two isomers, endo and exo (also known as I and II) | |
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C₉H₆Cl₆O₃S | |
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C1C2C(COS(=O)O1)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl | |
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C1[C@@H]2[C@H](COS(=O)O1)[C@@]3(C(=C([C@]2(C3(Cl)Cl)Cl)Cl)Cl)Cl | |
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RDYMFSUJUZBWLH-AZVNHNRSSA-N | |
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InChI=1S/C9H6Cl6O3S/c10-5-6(11)8(13)4-2-18-19(16)17-1-3(4)7(5,12)9(8,14)15/h3-4H,1-2H2 | |
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Yes |
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Common Name | Relationship | Link |
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enosulfan | Unstated isomer | ![]() |
General status |
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Insecticide, Acaricide | |
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Organochlorine | |
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- | |
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Synthetic | |
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Non-systemic with contact and stomach action, acts as a non-competitive GABA antagonist | |
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959-98-8 | |
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89 | |
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12309460 | |
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406.93 | |
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an equimolar mixture of 2 asymmetric, twisted-chair conformers of (5aR,6S,9R,9aS)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide | |
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equimolar mixture of 2 asymmetric, conformers of (5aR,6S,9R,9aS)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide | |
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(3α,5αβ,6α,9α,9αβ)-6,7,8,9,10,10-hexachloro-1,5,5α,6,9,9α-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide | |
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POP candidate; OSPAR pfa/soc; WFD priority substance; Chemical subject to PIC regulations | |
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EU Directive 2008/105/EC EQS surface waters: annual average 0.005 µg l⁻¹; max measured 0.01 µg l⁻¹ | |
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Not applicable | |
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Not applicable | |
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2A | |
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Not applicable | |
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None identified | |
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Brown crystals |
Formulations |
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0.32 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
Low | ||||||||
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200000 | C3 C = AGRITOX (click here ) Ethyl acetate3 = Unverified data of known source |
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6500 | C3 C = AGRITOX (click here ) Ethanol3 = Unverified data of known source |
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24000 | C3 C = AGRITOX (click here ) Hexane3 = Unverified data of known source |
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200000 | C3 C = AGRITOX (click here ) Toluene3 = Unverified data of known source |
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109.2 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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401.28 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
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5.50 X 1004 | Calculated | - | |||||||
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4.74 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
High | ||||||||
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8.3 | E3 E = Manufacturers safety data sheets 3 = Unverified data of known source |
Moderately volatile | ||||||||
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1.48 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately volatile | ||||||||
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Degradation |
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50 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately persistent | |||||||
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39 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately persistent | ||||||||
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86 | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Moderately persistent | ||||||||
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1.5 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published data RL₅₀ range 0.7-2.2 days, 4 field grown crops inc. peppers & tomatoes, various matrices, n=6 | ||||||||||
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1.4 | R4 R = Peer reviewed scientific publications 4 = Verified data |
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Published data RL₅₀ range 0.2-2.7 days, 3 field grown crops inc. peppers & tea, various matrices, n=4 | ||||||||||
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20 | C3 C = AGRITOX (click here ) 3 = Unverified data of known source |
Non-persistent | |||||||
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Soil adsorption and mobility |
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- | L3 L = Pesticide manuals and hard copy reference books / other sources 3 = Unverified data of known source |
Non-mobile | |||||||
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11500 | ||||||||||
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Fate indices |
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-0.12 | Calculated | Low leachability | ||||||||||||||||||||||||||
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5.35 X 10-03 | Calculated | - | |||||||||||||||||||||||||
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Estimated concentrations of chemicals with Koc values greater than 9995 ml g⁻¹ are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW | ||||||||||||||||||||||||||||
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High | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - |
Key metabolites |
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Soil | - | - |
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2755 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Whole fish3 = Unverified data of known source |
Threshold for concern | |||||||
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Not available | - | |||||||||
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38 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
High | ||||||||
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111 | L3 L = Pesticide manuals and hard copy reference books / other sources Anas platyrhynchos3 = Unverified data of known source |
Moderate | ||||||||
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0.002 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss3 = Unverified data of known source |
High | ||||||||
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0.44 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna3 = Unverified data of known source |
Moderate | ||||||||
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0.24 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Americamysis bahia3 = Unverified data of known source |
Moderate | ||||||||
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0.1 | F2 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Chironomus riparius 2 day2 = Unverified data of unknown source |
Moderate | ||||||||
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2.15 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Anabaena doliolum3 = Unverified data of known source |
Moderate | ||||||||
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7.81 | C3 C = AGRITOX (click here ) 3 = Unverified data of known source |
Moderate | |||||||
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14 | C3 C = AGRITOX (click here ) Eisenia foetida3 = Unverified data of known source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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38 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
High | ||||||||
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500 | R3 R = Peer reviewed scientific publications Rat3 = Unverified data of known source |
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0.013 | L3 L = Pesticide manuals and hard copy reference books / other sources Rat3 = Unverified data of known source |
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List I | - | - | ||||||||
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Can be absorbed following ingestion, inhalation and skin contact | ||||||||||
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Health issues |
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Mutagenic potential Highly toxic Endocrine toxicant |
Handling issues |
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Corrosive | |||
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T+ - Very toxic: R26/28 Xn - Harmful: R21 N - Dangerous for the environment: R50, R53 |
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S1/2, S28, S36/37, S45, S60, S61, S63 | |||
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II (Moderately hazardous) | |||
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alpha-endosulfan | ||
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alphaendosulfan | ||
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alpha-Endosulfan | ||
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alpha-endosulfan | ||
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alfaendosulfan | ||
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alfaendosulfan | ||
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alfa endosulphan | ||
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alfa-endosulfan | ||
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alpha endoszulfan | ||
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alfa-endosulfan |
Record last updated: | 16/12/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |