Aldrin (Ref: OMS 194) |
![]() Last updated: 16/12/2020 |
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(Also known as: HHDN; compound 118; octalene; ENT-16225; OMS-194) |
SUMMARY |
Aldrin is an obsolete organochlorine insecticide. It is banned from use in the EU and most of the developed world. It is virtually insoluble in water, quite volatile but unlikely to leach to groundwater. There are field studies that have shiown that aldrin can be persistent in soils. It is highly toxic to mammals and has a high potential for bioaccumulation. Aldrin is considered to be a carcinogen and neurotoxicant. It is highly toxic to most biodiversity. |
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An obsolete persistent organochlorine insecticide that was mainly used to control soil dwelling insects | |
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Termites; Wireworms; Rootworms; Weevils; Grasshoppers; White grubs; Corn root worm | |
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Corn; Alfalfa; Cotton; Vines; Bananas; Potted ornamentals | |
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Obsolete, Banned | |
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circa 1950 |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Yes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Chemical structure |
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A chiral molecule, aldrin is one of the several isomers of of hexachlorohexahydrodimethanonaphthalene. | |
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C₁₂H₈Cl₆ | |
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C1C2C=CC1C3C2C4(C(=C(C3(C4(Cl)Cl)Cl)Cl)Cl)Cl | |
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C1[C@@H]2C=C[C@H]1[C@H]3[C@@H]2[C@]4(C(=C([C@@]3(C4(Cl)Cl)Cl)Cl)Cl)Cl | |
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QBYJBZPUGVGKQQ-SJJAEHHWSA-N | |
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InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5-,6-,7+,10-,11-/m0/s1 | |
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Yes |
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Common Name | Relationship | Link |
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aldrin | Unstated isomer | ![]() |
General status |
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Insecticide | |
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Organochlorine | |
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Synthetic | |
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Central nervous system stimulant. GABA-gated chloride channel antagonist. Also stomach and contact toxin | |
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309-00-2 | |
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206-215-8 | |
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27 | |
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045101 | |
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12310947 | |
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364.91 | |
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(1R,4S,4aS,5S,8R,8aR)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8α-hexahydro-1,4:5,8-dimethanonaphthalene | |
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(1R,4S,4aS,5S,8R,8aR)-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8α-hexahydro-1,4:5,8-dimethanonaphthalene | |
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(1R,4S,4aS,5S,8R,8aR)-rel-1,2,3,4,10,10-hexachloro-1,4,4a,5,8,8α-hexahydro-1,4:5,8-dimethanonaphthalene | |
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WFD priority substance; Subject to PIC regulations; POP - regulated by Stockholm Convention; PAN Dirty Dozen; LRTAP Annex I; OSPAR soc; Marine Pollutant; Rotterdam Convention (Class O) | |
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EU Directive 2008/105/EC EQS sum of all cyclodiene pesticides in: inland surface waters: 0.01 µg l⁻¹; Other surface waters: 0.005 µg l⁻¹ as annual average | |
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Not applicable | |
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Not applicable | |
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2A | |
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Not applicable | |
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Agriotes lineatus, Agriotes obscurus, Anopheles annularis, Brontispa longissima, Cylas formicarius, plus others | |
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White to brown crystals | |
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Formulations |
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0.027 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Low | ||||||||
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6000000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Acetone4 = Verified data |
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6000000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Benzene4 = Verified data |
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6000000 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) Xylene4 = Verified data |
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104 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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145 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 3 = Unverified data of known source |
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Not expected to self ignite; Not highly flammable | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 3 = Unverified data of known source |
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3.16 X 1006 | Calculated | - | |||||||
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6.5 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
High | ||||||||
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1.6 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Not applicable | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
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No dissociation | |||||||||||
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8.6 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Moderately volatile | ||||||||
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1.72 X 1001 | V2 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 2 = Unverified data of unknown source |
Moderately volatile | ||||||||
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Degradation |
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28 | G4 G = Extension Toxicology network database EXTOXNET (click here ) 4 = Verified data |
Non-persistent | |||||||
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365 | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
Very persistent | ||||||||
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FAO state DT₅₀ 20-100 days | ||||||||||
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1.7 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Alfalfa leaves, n=1 | ||||||||||
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7.0 | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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Apples leaves, n=1 | ||||||||||
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Soil adsorption and mobility |
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- | H3 H = The US ARS pesticide properties database (click here ) 3 = Unverified data of known source |
Non-mobile | |||||||
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17500 | ||||||||||
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Other sources: 500 mL g⁻¹ (US3), 400-49000 mL g⁻¹ (R3) | ||||||||||
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Fate indices |
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-0.62 | Calculated | Low leachability | ||||||||||||||||||||||||||
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5.35 X 10-03 | Calculated | - | |||||||||||||||||||||||||
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Estimated concentrations of chemicals with Koc values greater than 9995 ml g⁻¹ are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW | ||||||||||||||||||||||||||||
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Medium | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - |
Key metabolites |
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Soil | - | Not assessed under 91/414 or 1107/2009 |
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3348 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) (literature data ranges Log BCF 2.3-5.1 (R3))3 = Unverified data of known source |
Threshold for concern | |||||||
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1-5 | - | |||||||||
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39 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
High | ||||||||
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6.6 | Q2 Q = Miscellaneous internet resources Colinus virginianus2 = Unverified data of unknown source |
High | ||||||||
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0.0046 | J3 J = Pesticide Action Network database (click here ) Lepomis macrochirus3 = Unverified data of known source |
High | ||||||||
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0.028 | J4 J = Pesticide Action Network database (click here ) Daphnia magna4 = Verified data |
High | ||||||||
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0.35 | F2 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 2 = Unverified data of unknown source |
High | ||||||||
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60 | F2 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 2 = Unverified data of unknown source |
Moderate | ||||||||
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General |
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High (class III) | - | - | ||||||||
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39 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Rat4 = Verified data |
High | ||||||||
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0.0001 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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0.003 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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List I | - | - | ||||||||
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May be absorbed through intact skin | ||||||||||
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0.03 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) PIC DGD - WHO recommendation max limit 0.03 µg l⁻¹5 = Verified data used for regulatory purposes |
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Health issues |
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Highly toxic by ingestion IARC group 3 carcinogen Endocrine issues - Competitive binding to androgen receptors |
Handling issues |
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No information available | |||
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Health: H301, H311, H351, H372 Environment: H400, H410 |
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Carcinogen category 3: R40 T - Toxic: R24/25, R48/24/25 N - Dangerous for the environment: R50, R53 |
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S1/2, S22, S45, S61, S36/37, S60 | |||
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O (Obsolete substance) | |||
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aldrin | ||
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aldrine | ||
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Aldrin | ||
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aldrin | ||
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aldrin | ||
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aldrin | ||
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aldrin | ||
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aldryna | ||
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aldrine |
Record last updated: | 16/12/2020 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |