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parathion (Ref: OMS 19)
** thiophos ** parathion-ethyl ** ENT 15108 ** BAY 9491 ** Translations

Environmental Fate - Ecotoxicology - Human Health - A to Z Index - Home

GENERAL INFORMATION
for parathion

Description: An insecticide and acaricide used to control sucking and chewing insects and mites

Introduction: circa 1950

EC Regulation 1107/2009 (repealing 91/414):
Status Not approved
Dossier rapporteur/co-rapporteur Italy
Date inclusion expires Expired

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:
Pesticide type Insecticide, Acaricide
Substance group Organophosphate
Substance origin Synthetic
Mode of action Non-systemic with contact, stomach and some respiratory action. Acetylcholinesterase (AChE) inhibitor.
CAS RN 56-38-2
EC number 200-271-7
CIPAC number 10
US EPA chemical code 057501
Chiral molecule No
Chemical formula C10H14NO5PS
SMILES S=P(Oc1ccc(cc1)[N+]([O-])=O)(OCC)OCC
International Chemical Identifier (InChI) InChI=1/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
Structure diagram/image available? Yes
Molecular mass (g mol-1) 291.26
PIN (Preferred Identification Name) -
IUPAC name O,O-diethyl O-4-nitrophenyl phosphorothioate
CAS name O,O-diethyl O-(4-nitrophenyl) phosphorothioate
Other status information PIC Annex III; Potential groundwater contaminant; Marine Pollutant; Rotterdam Convention (Class Ia)
Herbicide Resistance Classification (HRAC) Not applicable
Insecticide Resistance Classification (IRAC) 1B
Fungicide Resistance Classification (FRAC) Not applicable
Physical state Pale yellow liquid
Related substances & organisms -

Formulations:
Property Value
Example manufacturers of products using this active
  • King Tech
  • Fujian Sannong Group Co. Ltd.
  • Chimac-Agriphar S.A.
Example products using this active
  • Woprophos
  • Fighter
  • Co-thion
UK LERAP status No UK approval for use or outside scope
Formulation and application details Available in a variety of formulations including dusts, emulsion concentrates, granules, ULV liquids and wettable powders.


ENVIRONMENTAL FATE

for parathion

Property Value Source/Quality Score/Other Information Interpretation
Solubility - In water at 20oC (mg l-1) 12.4 G4 Low
Solubility - In organic solvents at 20oC (mg l-1) 200000 L3 - Dichloromethane -
200000 L3 - Toluene -
75000 L2 - Hexane -
200000 L3 - Isopropanol -
Melting point (oC) 6.1 L3 -
Boiling point (oC) 375 L3 -
Degradation point (oC) - - -
Flashpoint (oC) 174 L3 -
Octanol-water partition coefficient at pH 7, 20oC P 6.76 X 1003 Calculated -
Log P 3.83 G4 High
Bulk density (g ml-1)/Specific gravity 1.26 AC4 -
Dissociation constant (pKa) at 25oC - - -
Note:
Vapour pressure at 25oC (mPa) 0.89 L3 Non-volatile
Henry's law constant at 25oC (Pa m3 mol-1) 3.02 X 10-02 L3 Non-volatile
Henry's law constant at 20oC (dimensionless) 2.50 X 10-05 K3 Moderately volatile
GUS leaching potential index 2.09 Calculated Transition state
SCI-GROW groundwater index (μg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate Value 2.67 X 10-02 Calculated -
Note -
Potential for particle bound transport index - Calculated Medium
Maximum UV-vis absorption L mol-1 cm-1 - - -
Surface tension (mN m-1) - - -

Degradation:
Property Value Source/Quality Score/Other Information Interpretation
Soil degradation (days) (aerobic) DT50 (typical) 49 K4 Moderately persistent
DT50 (lab at 20oC) 14 F3 Non-persistent
DT50 (field) 17 AC4 Non-persistent
DT90 (lab at 20oC) - - -
DT90 (field) - - -
Note ICULID datasheet DT50 lab studies 3-32 days, field studies DT50 range 2-58 days; Other sources: 7DT50 -10 days (R3)
Aqueous photolysis DT50 (days) at pH 7 Value 30 AC4 Stable
Note -
Aqueous hydrolysis DT50 (days) at 20oC and pH 7 Value 260 L3 Persistent
Note pH sensitive: DT50 272 days at pH 4, 130 days at pH 9, all at 22 degC
Water-sediment DT50 (days) 4.3 K4 Fast
Water phase only DT50 (days) 3.5 K4 Moderately fast

Soil adsorption and mobility:
Property Value Source/Quality Score/Other Information Interpretation
Linear Kd - H3 Non-mobile
Koc 7660
Notes and range Other sources: 316.2-15849 mL/g (R3)
Freundlich Kf 17 R4 Slightly mobile
Kfoc 580
1/n 0.95
Notes and range Kf range 13.0-21.0 (229 for peat) mL/g, Kfoc range 491-636 (355 for peat) mL/g, 1/n - no data, Soils=4
pH sensitivity -


ECOTOXICOLOGY

for parathion

Property Value Source/Quality Score/Other Information Interpretation
Bio-concentration factor BCF 40 P4 (Other literature values Log BCF range 1.1-1.9 (R3)) Low potential
CT50 (days) <0.5 -
Bioaccumulation potential - Calculated Low
Mammals - Acute oral LD50 (mg kg-1) 2 G4 Rat High
Mammals - Short term dietary NOEL (mg kg-1) - L2 Rat, 2 year -
(ppm diet) 2 -
Birds - Acute LD50 (mg kg-1) 2.1 G4 Anas platyrhynchos High
Birds - Short term dietary (LC50/LD50) - - -
Fish - Acute 96 hour LC50 (mg l-1) 1.5 L3 Oncorhynchus mykiss Moderate
Fish - Chronic 21 day NOEC (mg l-1) - - -
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1) 0.0025 L3 Daphnia magna High
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1) - - -
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1) 0.00011 F4 Americamysis bahia High
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1) 0.14 F3 Chironomus riparius, 1 day Moderate
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1) - - -
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1) - - -
Aquatic plants - Acute 7 day EC50, biomass (mg l-1) - - -
Algae - Acute 72 hour EC50, growth (mg l-1) 0.5 L3 Scenedemus subspicatus Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1) - - -
Honeybees - Acute 48 hour LD50 (μg bee-1) > 0.21 R4 Oral High
Earthworms - Acute 14 day LC50 (mg kg-1) > 267 L3 Eisenia foetida Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1) - - -
Other soil macro-organisms - e.g. Collembola LR50 / EC50 / NOEC / % Effect - - -
Other arthropod (1) LR50 g ha-1 - - -
% Effect Harmful AB1 Typhlodromus pyri Harmful
Other arthropod (2) LR50 g ha-1 - - -
% Effect - - -
Soil micro-organisms - - -
Mesocosm study data NOEAEC mg l-1 - - -
NOEAEC mg l-1 - - -


HUMAN HEALTH AND PROTECTION

for parathion

General:
Property Value Source/Quality Score/Other Information Interpretation
Mammals - Acute oral LD50 (mg kg-1) 2 G4 Rat High
Mammals - Dermal LD50 (mg kg-1 body weight) 71.0 L3 Rat -
Mammals - Inhalation LC50 (mg l-1) 0.03 L3 Rat (aerosol) -
Other Mammal toxicity endpoints - -
ADI - Acceptable Daily Intake (mg kg-1bw day-1) 0.004 JMPR 1995 -
ARfD - Acute Reference Dose (mg kg-1bw day-1) - - -
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1) - - -
Dermal penetration studies (%) - - -
Dangerous Substances Directive 76/464 List I; List II - -
Exposure Limits - - -
Exposure Routes Public -
Occupational -
Examples of European MRLs (mg kg-1) Value -
Note For the EU pesticides database click here
Drinking Water MAC (μg l-1) - - -

Health issues:
Carcinogen Mutagen Endocrine disrupter Reproduction / development effects Acetyl cholinesterase inhibitor Neurotoxicant Respiratory tract irritant Skin irritant Eye irritant

-

-

-

General human health issues Highly toxic
Possible brain toxicant

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:
Property Value Source/Quality Score/Other Information Interpretation
General IMDG Transport Code is usually 6.1
CLP classification 2013 -
EC Risk Classification T+ - Very toxic: R26/28
T - Toxic: R24, R48/25
N - Dangerous for the environment: R50, R53
EC Safety Classification S1/2, S28, S36/37, S45, S60, S61
WHO Classification Ia - Extremely hazardous
US EPA Classification (formulation) I - Danger - Highly toxic
UN Number 3018
Waste disposal & packaging Packaging Group I (great danger)


TRANSLATIONS

for parathion

Language Name
English parathion
French parathion
German Parathion
Danish parathion
Italian paration
Spanish paratión
Greek parathion
Slovenian paration
Polish paration
Swedish -
Hungarian -
Dutch parathion

Record last updated: Saturday 17 August 2013
Contact: aeru@herts.ac.uk