Sulphachlorpyridazine
Last updated: 26/04/2021
(Also known as: sulfachlorpyridazine; BA-10370)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
An antibacterial / antibiotic veterinary medicine used to control a range of infections in pigs, poultry and claves
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Pigs, Poultry, Calves
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C₁₀H₉ClN₄O₂S
C1=CC(=CC=C1N)S(=O)(=O)NC2=NN=C(C=C2)Cl
No data
XOXHILFPRYWFOD-UHFFFAOYSA-N
InChI=1S/C10H9ClN4O2S/c11-9-5-6-10(14-13-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)
Yes
Cambridge Crystallographic Data Centre diagrams
Common Name
Relationship
Link
sulphachlorpyridazine
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Antibiotic, Microbiocide, Antimicrobial, Antibacterial
Sulfonamide
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Synthetic
Inhibits folic acid synthesis in prokaryotes
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80-32-0
201-269-9
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QJ01EW12
Antiinfectants for systemic use: Antibacterials for systemic use
No
Allowed substance (Table 1: All food producing species)
284.72
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4-amino-N-(6-chloropyridazin-3-yl)benzenesulfonamide
4-amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide
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Cosumix Plus powder for oral solution
Novartis Animal Health Ltd
UK National authorisation
None - expired
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7000
High
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187
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2.04 X 1000
Calculated
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0.31
R4 R = Peer reviewed scientific publications 4 = Verified data
Low
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1.40
R4 R = Peer reviewed scientific publications 4 = Verified data
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17
R4 R = Peer reviewed scientific publications 4 = Verified data
Non-persistent
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General literature states DT₅₀ range 3.5-21 days
<8.0
R4 R = Peer reviewed scientific publications 4 = Verified data
Slightly persistent; Other data 127 days for slurry
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Soil adsorption and mobility
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R4 R = Peer reviewed scientific publications 4 = Verified data
Mobile
43
General literature states Koc range 3.3-82 mL g⁻¹
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2.91
Calculated
High leachability
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None
Terrestrial ecotoxicology
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535.7
R4 R = Peer reviewed scientific publications 4 = Verified data
Oryzias latipes
Low
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0.375
R4 R = Peer reviewed scientific publications 4 = Verified data
Daphnia magna
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
?Possibly, status not identified
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
✓Yes, known to cause a problem
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
Ingestion of sulfonamide can cause nausea, vomiting & diarrhoea Possible kidney, gastrointestinal & liver toxicant
Light sensitive
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Not listed (Not listed)
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sulphachlorpyridazine
sulfachlorpyridazine
Sulfachlorpyridazine
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sulfacloropiridazina
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Record last updated:
26/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242