Monensin
Last updated: 21/04/2021
(Also known as: monensic acid)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
 
A broad spectrum antibotic and coccidiostat drug also used as a growth promotor
Current
1979, first synthesised
Poultry, Cattle
No data
C₃₆H₆₂O₁₁
CCC1(CCC(O1)C2(CCC3(O2)CC(C(C(O3)C(C)C(C(C)C(=O)O)OC)C)O)C)C4C(CC(O4)C5C(CC(C(O5)(CO)O)C)C)C
CC[C@]1(CC[C@@H](O1)[C@]2(CC[C@@]3(O2)C[C@@H]([C@H]([C@H](O3)[C@H](C)[C@@H]([C@@H](C)C(=O)O)OC)C)O)C)[C@@H]4[C@@H](C[C@H](O4)[C@@H]5[C@H](C[C@H]([C@@](O5)(CO)O)C)C)C
GAOZTHIDHYLHMS-GDMSFIFLSA-N
InChI=1S/C36H62O11/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40)/t19-,20+,21+,22+,23+,24+,25-,26-,27+,28-,29-,30-,31-,33+,34-,35+,36-/m0/s1
Yes
Antibiotic, Antibacterial, Coccidiostat, Feed additive, Growth promotor
Polyether (ionophore)
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Natural
A protein transport inhibitor
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17090-79-8
241-154-0
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QP51AH03
Antiparasitic products, insecticides & repellents: Antiprotozoals
No
Allowed substance (Table 1: Bovine)
670.87
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4-[2-[5-ethyl-5-[5-[6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-oxan-2-yl]-3-methyl-oxolan-2-yl]oxolan-2-yl]- 9-hydroxy-2,8-dimethyl-1,6-dioxasp iro[4.5]dec-7-yl]-3-methoxy-2-methyl-pentanoic acid
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White crystalline solid
Coxidin
Huvepharma NV Belgium
Annex 1 Reg 109/2007; Annex 2 Reg 156/2008; Annex 3 Reg 1095/2008
Not applicable
Elancoban G200 & G100
Eli Lilly & Co
Annex 1 Reg 1356/2004; Annex 2 & 4 Reg 108/2007; Annex 3 Reg 1096/2008
Not applicable
Usually supplied as a premix or feed additive
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104
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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2.69 X 1005
Calculated
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5.43
High
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4.27 X 10-18
Low volatility
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7.4
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Non-persistent
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General literature: 1ppm soil conc, only trace remained after 20 days (R4)
5.8
R3 R = Peer reviewed scientific publications 3 = Unverified data of known source
Soil & cattle manure
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Soil adsorption and mobility
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Known soil and groundwater metabolites
None
monensin methyl ester
MME
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monensin decyl ester
MDE
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Terrestrial ecotoxicology
100
Rat
Moderate
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10
R4 R = Peer reviewed scientific publications 4 = Verified data
Moderate
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9
R4 R = Peer reviewed scientific publications 4 = Verified data
Oncorhynchus mykiss
Moderate
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10.7
R4 R = Peer reviewed scientific publications 4 = Verified data
Daphnia magna
Moderate
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HUMAN HEALTH AND PROTECTION
High (class III)
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100
Rat
Moderate
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Intraperitoneal LD₅₀ = 15 mg kg⁻¹
Rat
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Excreted rapidly in the faeces and urine
Q3 Q = Miscellaneous data from online sources 3 = Unverified data of known source
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E2 E = Unspecified genotoxicity type (miscellaneous data source) 2 = Mixed/ambiguous results
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
No data found
XNo, known not to cause a problem
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
✓Yes, known to cause a problem
No data found
Eye irritant
Phototoxicant
 
✓Yes, known to cause a problem
No data found
 
May cause pulmonary edema May cause gastroinstinal and renal function problems
When heated to decomposition it emits acrid smoke & irritating fumes
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Not listed (Not listed)
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monensin
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monensina
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Record last updated:
21/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242