Emamectin B1b |
Last updated: 31/05/2024 |
(Not known by any other names) |
Data alerts |
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate | Ecotoxicity | Human health |
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A naturally occuring soil Actinomycete effective against various soft-bodied insects | |
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Caterpillars; Mites; Thrips; Leaf miners | |
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Fruit trees; Leafy crops including lettuce, brassicas | |
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Current | |
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1997, introduced Israel and Japan; 1999, introduced USA | |
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GB regulatory status |
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Approved | ||
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30/11/2024 | ||
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No UK approval for use as a pesticide |
EC Regulation 1107/2009 (repealing 91/414) |
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Approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Netherlands | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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30/11/2024 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Additional information |
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Chemical structure |
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Emamectin B1b is a complex molecule with multiple chiral centres. | |
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C₄₈H₇₃NO₁₃ | |
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CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)NC)OC)OC)C)OC7(C4)C=CC(C(O7)C(C)C)C)O | |
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C[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@@H]([C@@H](O6)C)NC)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C(C)C)C)O | |
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DXIOOXFZLKCVHK-VAUHGISYSA-N | |
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InChI=1S/C48H73NO13/c1-25(2)42-28(5)17-18-47(62-42)23-34-20-33(61-47)16-15-27(4)43(26(3)13-12-14-32-24-55-45-41(50)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-11)44(31(8)57-39)60-38-21-36(53-10)40(49-9)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,16,20-24H2,1-11H3/b13-12+,27-15+,32-14+/t26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41+,42+,43-,44-,45+,47+,48+/m0/s1 | |
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Yes |
General status |
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Fungicide, Other substance, Veterinary substance | |
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Bactericide | |
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Micro-organism derived substance | |
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Non-systemic, acts by causing insect paralysis. Glutamate-gated chloride channel (GluCl) allosteric modulator. | |
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Produced by the fermentation of the soil actinomycete Streptomyces avermitilis | |
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Crop protection | |
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Caterpillars; Mites; Thrips; Leaf miners | |
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Fruit trees; Leafy crops including lettuce, brassicas | |
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121424-52-0 | |
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791 | |
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872.1 | |
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(10E,14E,16E)-(1R,4S,5S,6S,6R,8R,12S,13S,20R,21R,24S)-21,24-dihydroxy--6-isopropyl-5,11,13,22-tetramethyl-2-oxo-(3,7,19-trioxatetracyclo[15.6.1.1.0]pentacosa-10,14,16,22-tetraene)-6-spiro-2Œ-(5,6-dihydro-2H-pyran)-12-yl 2,6-dideoxy-3-O-methyl-4-O-(2,4,6-trideoxy-3-O-methyl-4-methylamino-α-L-lyxo-hexapyranosyl)-)-α-L-arabino-hexapyranoside | |
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(4R)-5-O-demethyl-25-de(1-methylpropyl)-4-deoxy-4-(methylamino)-25-(1-methylethyl)-avermectin A1a | |
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Not applicable | |
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Not applicable | |
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6 | |
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BM02 | |
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White or faintly yellow powder | |
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Formulations |
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21 | A4 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 4 = Verified data |
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1.00 X 1005 | Calculated | - | |||||||
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5.0 | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Soluble | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Regulatory data - observed in metabolism and farm animal feeding studies | A5 A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. EU Annex III PIC DGD) (EU - Pesticides database; EFSA Scientific Publications ) 5 = Verified data used for regulatory purposes |
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Degradation |
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As this parameter is not normally measured directly, a surrogate measure is used: ‘Photochemical oxidative DT₅₀’. Where data is available, this can be found in the Fate Indices section below. | ||||||||||
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Soil adsorption and mobility |
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Known soil metabolites |
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Known groundwater metabolites |
None
Other known metabolites |
None
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Terrestrial ecotoxicology |
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Aquatic ecotoxicology |
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General |
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Health issues |
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May cause climical tremors |
Handling issues |
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Not explosive or oxidising Not explected to auto-ignite, Not highly flammable |
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Health: H301, H311, H331, H372, H318, H319 Environment: H400 |
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Not listed (Not listed) | |||
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emamectin B1b | ||
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Record last updated: | 31/05/2024 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |