1,2,4-triazole (Ref: CGA 71019) ** 1H-1,2,4-triazole ** BF 480-16 ** RH-0118 ** 1,2,4-T ** AE C500859 ** Translations

Environmental Fate - Ecotoxicology - Human Health

GENERAL INFORMATION

Description: Chemical transformation product

Introduction: Not applicable

EC Directive 1107/2009 (repealing 91/414):

Status	Not applicable
Dossier rapporteur/co-rapporteur	Not applicable
Date inclusion expires	Not applicable

Approved for use () or known to be used () in the following European countries:

AT

BE

BG

CY

CZ

DE

DK

EE

EL

ES

FI

FR

HU

IE

IT

LT

LU

LV

MT

NL

PL

PT

RO

SE

SI

SK

UK

General status:

Pesticide type	Metabolite
Metabolite Type	Soil, Groundwater, Plants, Animals
Substance group	Triazole
Substance origin	Synthetic
Mode of action	Not applicable
CAS RN	288-88-0
EC number	206-022-9
CIPAC number	-
US EPA chemical code	Not applicable
Chemical formula	C2H3N3
SMILES	n1cnnc1
International Chemical Identifier (InChI)	InChI=1/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)
Structure diagram/image available?	Yes
Molecular mass (g mol-1)	69.03
IUPAC Name	1H-1,2,4-triazole
CAS Name	1,2,4-triazole
Other status information	-
Herbicide Resistance Classification (HRAC)	Not applicable
Insecticide Resistance Classification (IRAC)	Not applicable
Fungicide Resistance Classification (FRAC)	Not applicable
Physical state	-
Related substances & organisms	climbazole

Can be a metabolite of:

Parent		Formation Medium	Estimated Maximum Occurrence Fraction	91/414 Relevancy
penconazole		Soil	0.386	Major fraction, Relevant
amitrole		Soil		Major fraction
hexaconazole		Soil		Not relevant
myclobutanil		Soil		Minor fraction
cyproconazole		Soil	0.170	Major fraction, Not relevant
epoxiconazole		Soil	0.066	Minor fraction, Relevant
fenbuconazole		Soil	0.124	Major fraction, Relevant
propiconazole		Soil	0.430	Major fraction, Relevant
bitertanol		Soil	0.44	Major fraction, Relevant
ipconazole		Soil	0.119	Relevant, Major fraction
tebuconazole		Soil	0.09	Minor fraction, Relevant
fluquinconazole		Soil	0.189	Major fraction, Relevant
paclobutrazol		Soil	0.03	Minor fraction, Relevant
difenoconazole		Soil	0.23	Major fraction, Relevancy unknown
triadimenol		Soil	1.00	Major fraction, Relevant

Formulations:

Property	Value
Example manufacturers of products using this active	Not applicable
Example products using this active	-
UK LERAP status	Not applicable
Formulation and application details	-

ENVIRONMENTAL FATE

Property		Value	Source/Quality Score/Other Information	Interpretation
Solubility - In water at 20oC (mg l-1)		730000	A5	High
Solubility - In organic solvents at 20oC (mg l-1)		-	-	-
Melting Point (oC)		121	Q2	-
Boiling Point (oC)		-	-	-
Degradation point (oC)		-	-	-
Flashpoint (oC)		-	-	-
Octanol-water partition coefficient at pH 7, 20oC	P	1.00 X 10-01	Calculated	-
	Log P	-1.0	A4	Low
Bulk density (g ml-1)/Specific gravity		-	-	-
Dissociation constant (pKa) at 25oC		2.2	Q3	-
		Note: Strong acid
Vapour pressure at 25oC (mPa)		0.022	A4	Non-volatile
Henry's law constant at 25oC (Pa m3 mol-1)		0.155	V3	Moderately volatile
Henry's law constant at 20oC (dimensionless)		8.54 X 10-13	Calculated	Non-volatile
GUS leaching potential index		1.95	Calculated	Transition state
SCI-GROW groundwater index (µg l-1) for a 1 kg ha-1 or 1 l ha-1 application rate	Value	3.41 X 10-02	Calculated	-
	Note	-
Potential for particle bound transport index		-	Calculated	Low
Maximum UV-vis absorption L mol-1 cm-1		-	-	-
Surface tension (mN m-1)		-	-	-

Degradation:

Property		Value	Source/Quality Score/Other Information	Interpretation
Soil degradation (days) (aerobic)	DT50 (typical)	10	A5	Non-persistent
	DT50 (lab at 20oC)	8.2	A5	Non-persistent
	DT50 (field)	-	-	-
	DT90 (lab at 20oC)	31	A5	-
	DT90 (field)	-	-	-
	Note	EU dossiers of the various parents give Lab values DT50 range 5.0-9.9 days, DT90 range 21-41 days; Focus studies DT50 7.0-13.3 days
Aqueous photolysis DT50 (days) at pH 7	Value	Stable	A3	Stable
	Note	-
Aqueous hydrolysis DT50 (days) at 20oC and pH 7	Value	Stable	A5	Very persistent
	Note	Stable pH 5 to pH 9, 25 degC
Water-Sediment DT50 (days)		300	A4	Slow
Water phase only DT50 (days)		300	A4	Stable

Soil adsorption and mobility:

Property		Value	Source/Quality Score/Other Information	Interpretation
Linear	Kd	-	-	-
	Koc	-
	Notes and range	-
Freundlich	Kf	0.719	A4	Moderately mobile
	Kfoc	112
	1/n	0.91
	Notes and range	EU dossier kf range 0.234-0.833, kfoc range 43-202 mL/g, 1/n range 0.827-1.016, Soils=5
pH sensitivity		No

ECOTOXICOLOGY

Property		Value	Source/Quality Score/Other Information	Interpretation
Bio-concentration factor	BCF	-	-	-
	CT50 (days)	-		-
Bioaccumulation potential		-	Calculated	Low
Mammals - Acute oral LD50 (mg kg-1)		> 1650	A5 Rat	Moderate
Mammals - Short term dietary NOEL	(mg kg-1)	-	-	-
	(ppm diet)	-		-
Birds - Acute LD50 (mg kg-1)		316	V3 Phasianidae	Moderate
Birds - Short term dietary (LC50/LD50)		-	-	-
Fish - Acute 96 hour LC50 (mg l-1)		498	A5 Oncorhynchus mykiss	Low
Fish - Chronic 21 day NOEC (mg l-1)		3.2	A5 Oncorhynchus mykiss	-
Aquatic invertebrates - Acute 48 hour EC50 (mg l-1)		> 100	A5 Daphnia magna	Moderate
Aquatic invertebrates - Chronic 21 day NOEC (mg l-1)		-	-	-
Aquatic crustaceans - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Acute 96 hour LC50 (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l-1)		-	-	-
Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg-1)		-	-	-
Aquatic plants - Acute 7 day EC50, biomass (mg l-1)		-	-	-
Algae - Acute 72 hour EC50, growth (mg l-1)		8.2	A5 Pseudokirchneriella subcapitata	Moderate
Algae - Chronic 96 hour NOEC, growth (mg l-1)		-	-	-
Honeybees - Acute 48 hour LD50 (µg bee-1)		-	-	-
Earthworms - Acute 14 day LC50 (mg kg-1)		> 1000	A5 Eisenia foetida	Moderate
Earthworms - Chronic 14 day NOEC, reproduction (mg kg-1)		0.071	A5 Eisenia foetida	High
Other soil macro-organisms - e.g. Collembola	LR50product ha EC50product ha NOECproduct ha % Effect	1.8	A4 Folsomia candida, 28 day NOEC mg kg-1	-
Other arthropod (1)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Other arthropod (2)	LR50 g ha-1	-	-	-
	% Effect	-	-	-
Soil micro-organisms		Nitrogen mineralisation: No significant effect Carbon mineralisation: No significant effect	A5 Dose: 0.353 mg/kg soil, 28 days	-
Mesocosm study data	NOEAEC mg l-1	-	-	-
	NOEAEC mg l-1	-	-	-

HUMAN HEALTH AND PROTECTION

General:

Property		Value	Source/Quality Score/Other Information	Interpretation
Mammals - Acute oral LD50 (mg kg-1)		> 1650	A5 Rat	Moderate
Mammals - Dermal LD50 (mg kg-1 body weight)		-	-	-
Mammals - Inhalation LC50 (mg l-1)		-	-	-
Other Mammal toxicity endpoints		-		-
ADI - Acceptable Daily Intake (mg kg-1bw day-1)		-	-	-
ARfD - Acute Reference Dose (mg kg-1bw day-1)		-	-	-
AOEL - Acceptable Operator Exposure Level - Systemic (mg kg-1bw day-1)		-	-	-
Dermal penetration studies (%)		-	-	-
Dangerous Substances Directive 76/464		-	-	-
Exposure Limits		-	-	-
Exposure Routes	Public	-
	Occupational	-
Examples of European MRLs (mg kg-1)	Value	-
	Note	For the EU pesticides database click here
Drinking Water MAC (µg l-1)		-	-	-

Health issues:

Carcinogen	Mutagen	Endocrine disrupter	Reproduction / development effects	Acetyl cholinesterase inhibitor	Neurotoxicant	Respiratory tract irritant	Skin irritant	Eye irritant
-	-	-		-	-	-
General human health issues		[No further information available]

: Yes, known to cause a problem
: No, known not to cause a problem
: Possibly, status not identified
- : No data

Handling issues:

Property		Value	Source/Quality Score/Other Information	Interpretation
General		[No information available]
EC Risk Classification		[Reproduction risk category 3: R63], [Xn - Harmful: R22], [Xi - Irritant: R36]
EC Safety Classification		S2, S36/37
WHO Classification		NL	-	Not listed
US EPA Classification (formulation)		Not applicable	-	-
UN Number		-
Waste disposal & packaging		-

TRANSLATIONS