DDD (Ref: ENT 4225) |
![]() Last updated: 07/01/2021 |
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(Also known as: dichlorodiphenyldichloroethane; tetrachlorodiphenylethane; TDE; p,p'-DDD; ME-1700) |
SUMMARY |
DDD is a banned and obsolete insecticide that is also a metabolite of DDT. It is practically insoluble in water and is not highly volatile. It is, like DDT, very environmentally perssitent in both soils and water. It is toxic to humans through ingestion, inhalation and via skin absorption and has been linked with cancer, is mutagenic and various negative reproduction/fertility effects. It is also an endocrine disrupter. It is toxic to most animal species but data is not abundant. |
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A now obsolete insecticide that was formerly used to kill a wide range of insect pests especially those that carry disease. It is also a pesticide transformation product of DDT | |
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Mosquitoes; Lice | |
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Vegetables; Cotton; Peanuts; Forestry; Public health situations | |
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Not applicable | |
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Obsolete, banned | |
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1944, first reported |
UK regulatory status |
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Not approved | ||
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Not applicable | ||
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No UK approval for use |
EC Regulation 1107/2009 (repealing 91/414) |
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Not approved | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Not applicable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Also used in |
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Chemical structure |
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Consists of three isomeric forms p,p'-DDD, o,p'-DDD and o,o'-DDD. p,p'-DDD is the dominant isomer. | |
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C₁₄H₁₀Cl₄ | |
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C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl | |
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No data | |
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AHJKRLASYNVKDZ-UHFFFAOYSA-N | |
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InChI=1S/C14H10Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8,13-14H | |
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Yes |
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Common Name | Relationship | Link |
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DDD | - | ![]() |
General status |
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Insecticide, Metabolite | |
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Soil | |
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Organochlorine | |
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Synthetic | |
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Non-systemic stomach and contact action | |
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72-54-8 | |
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200-783-0 | |
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199 | |
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029101 | |
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6294 | |
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320.04 | |
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- | |
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1,1-dichloro-2,2-bis(4-chlorophenyl)ethane | |
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1,1'-(2,2-dichloroethylidene)bis(4-chlorobenzene) | |
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Common environmental pollutant | |
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- | |
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Not applicable | |
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Not applicable | |
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2A | |
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Not applicable | |
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- | |
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Clear to off-white coloured crystals |
Can be a metabolite of: |
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DDT | Soil | - | Not assessed under 91/414 or 1107/2009 | |||||
p,p'-DDT | Soil | - | Not assessed under 91/414 or 1107/2009 | |||||
o,p'-DDT | Soil | - | Not assessed under 91/414 or 1107/2009 | |||||
o,o'-DDT | Soil | - | Not assessed under 91/414 or 1107/2009 |
Formulations |
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0.09 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Low | ||||||||
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110 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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350 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Not expected to self ignite; Not highly flammable | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 3 = Unverified data of known source |
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1.05 X 1006 | Calculated | - | |||||||
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6.02 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
High | ||||||||
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1.385 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Not applicable | R3 R = Peer reviewed scientific publications 3 = Unverified data of known source |
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No dissociation | |||||||||||
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0.18 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) at 25 °C3 = Unverified data of known source |
Low volatility | ||||||||
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4.0 X 10-06 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
Non-volatile | ||||||||
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Degradation |
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Not considered to be biodegradeable. | ||||||||||
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1000 | F3 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 3 = Unverified data of known source |
Very persistent | |||||||
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160 | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
Persistent | ||||||||
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Environmentally stable | ||||||||||
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Stable | Q3 Q = Miscellaneous internet resources 3 = Unverified data of known source |
Stable | |||||||
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Soil adsorption and mobility |
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- | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) 3 = Unverified data of known source |
Non-mobile | |||||||
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131000 | ||||||||||
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Literature data ranges 130600 to 131800 mL g⁻¹ | ||||||||||
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Fate indices |
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-2.46 | Calculated | Low leachability | ||||||||||||||||||||||||||
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5.35 X 10-03 | Calculated | - | |||||||||||||||||||||||||
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Estimated concentrations of chemicals with Koc values greater than 9995 ml g⁻¹ are beyond the scope of the regression data used in SCI-GROW development. If there are concerns for such chemicals, a higher tier groundwater exposure assessment should be considered, regardless of the concentration returned by SCI-GROW | ||||||||||||||||||||||||||||
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High | Calculated | - | ||||||||||||||||||||||||||
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Non-mobile | Calculated | - |
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113 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
Moderate | ||||||||
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> 4814 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Anas platyrhynchos4 = Verified data |
Low | ||||||||
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> 0.07 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Oncorhynchus mykiss4 = Verified data |
High | ||||||||
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> 0.009 | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) Daphnia magna4 = Verified data |
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General |
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High (class III) | - | - | ||||||||
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113 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
Moderate | ||||||||
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1200 | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rabbit3 = Unverified data of known source |
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Percutaneous LD₅₀ > 10000 mg kg⁻¹ | V3 V = ChemID online databases / IPCS INCHEM (ChemID; IPCS INCHEM ) Rat3 = Unverified data of known source |
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List I | - | - | ||||||||
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Risk from residues in food but the substance is now banned | |||||||||
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PPE/PPC essential | ||||||||||
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US drinking water standards are variable by State: Minnesota 1.0 µg l⁻¹, Florida 0.1 µg l⁻¹ | F4 F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (US EPA Databases Related to Pesticide Risk Assessment ) 4 = Verified data |
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Health issues |
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Moderately toxic by ingestion, inhalation and skin absorption Endocrine issues - Competitive binding to androgen receptors Whilst DDD is linked with cancer one particular isomeric form (o,p'-DDD) has been used to treat cancer of the adrenal gland |
Handling issues |
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Combustible Incompatible with alkalis, strong oxidisers |
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Health: H301, H312, H351 Environment: H400, H401 |
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Not classified: Obsolete | |||
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Not classified: Obsolete | |||
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O (Obsolete substance) | |||
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2761 | |||
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DDD | ||
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TDE | ||
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TDE | ||
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TDE | ||
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TDE | ||
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TDE | ||
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dichlorodifenylodichloroetan | ||
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TDE |
Record last updated: | 07/01/2021 |
Contact: | aeru@herts.ac.uk |
Please cite as: | Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050-1064. DOI: 10.1080/10807039.2015.1133242 |