Ormetoprim
Last updated: 23/04/2021
(Also known as: ormethoprim)
The following alerts are based on the data in the tables below. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement.
Environmental fate
Ecotoxicity
Human health
A drug used in potentiated sulfonamide mixtures used as coccidiostats
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Poultry, Fish, Sheep
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C₁₄H₁₈N₄O₂
CC1=CC(=C(C=C1CC2=CN=C(N=C2N)N)OC)OC
No data
KEEYRKYKLYARHO-UHFFFAOYSA-N
InChI=1S/C14H18N4O2/c1-8-4-11(19-2)12(20-3)6-9(8)5-10-7-17-14(16)18-13(10)15/h4,6-7H,5H2,1-3H3,(H4,15,16,17,18)
Yes
Antimicrobial, Antibiotic, Medicinal drug
Diaminopyrimidine
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Synthetic
Interferes with folic acid production by inhibition of dihydrofolate reductase
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6981-18-6
230-246-6
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No
No data
274.32
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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
2,4-diamino-5-(6-methylveratryl)pyrimidine
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None identified
None identified
No UK authorisation for use with animals
No applicable
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1540
R4 R = Peer reviewed scientific publications 4 = Verified data
High
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1.70 X 1001
Calculated
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1.23
R4 R = Peer reviewed scientific publications 4 = Verified data
Low
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R2 R = Peer reviewed scientific publications 2 = Unverified data of unknown source
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Weak base
3.03 X 10-03
R4 R = Peer reviewed scientific publications 4 = Verified data
Low volatility
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Soil adsorption and mobility
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R4 R = Peer reviewed scientific publications 4 = Verified data
Slightly mobile
3687
Koc 2517 mL g⁻¹ soil with 81.5% sand, 4856 mL g⁻¹ soil with 52% sand
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None
Terrestrial ecotoxicology
665
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Moderate
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400
Salmo gairdneri
Low
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33
Daphnia magna
Moderate
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-
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90
Selenastrum capricornutum
Low
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HUMAN HEALTH AND PROTECTION
High (class III)
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665
E3 E = Manufacturers safety data sheets 3 = Unverified data of known source
Rat
Moderate
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Carcinogen
Endocrine disruptor
XNo, known not to cause a problem
A0 A = Chromosome aberration (EFSA database) 0 = No data
; B0 B = DNA damage/repair (EFSA database) 0 = No data
; C0 C = Gene mutation (EFSA database) 0 = No data
; D0 D = Genome mutation (EFSA database) 0 = No data
; E3 E = Unspecified genotoxicity type (miscellaneous data source) 3 = Negative
No data found
Reproduction / development effects
Acetyl cholinesterase inhibitor
Neurotoxicant
?Possibly, status not identified
No data found
No data found
Respiratory tract irritant
Skin irritant
Skin sensitiser
No data found
XNo, known not to cause a problem
No data found
Eye irritant
Phototoxicant
 
XNo, known not to cause a problem
No data found
 
No further information available
No information available
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None - not a ppp
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ormetoprim
ormetoprime
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ormetoprima
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Record last updated:
23/04/2021
Contact:
aeru@herts.ac.uk
Please cite as:
Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. (2016) An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal , 22 (4), 1050-1064. DOI: 10.1080/10807039.2015.1133242